Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13724563 | 0.84 | KMT2A (0.49) | KMT2AMEN1MAPTMAPK1RXFP1 | |
| SCHEMBL1122234 | 0.80 | KMT2A (0.56) | KMT2AMEN1MAPTMAPK1RXFP1 | |
| SCHEMBL631776 | 0.77 | KCNH3 (0.64) | KMT2AMEN1MAPTMAPK1RXFP1 | |
| SCHEMBL28520010 | 0.76 | RAB9A (0.54) | KMT2AMEN1MAPTMAPK1KCNH3 | |
| SCHEMBL8326648 | 0.76 | KMT2A (0.60) | KMT2AMEN1MAPTMAPK1RXFP1 | |
| SCHEMBL1085867 | 0.76 | MEN1 (0.71) | KMT2AMEN1MAPTMAPK1RXFP1 | |
| Hydrochloric Acid SCHEMBL2249099 | 0.76 | KCNH3 (0.67) | KMT2AMEN1MAPTMAPK1RXFP1 | |
| Bromide SCHEMBL20984930 | 0.75 | ALDH1A1 (0.57) | KMT2AMEN1MAPTMAPK1RXFP1 | |
| SCHEMBL10436614 | 0.74 | ALDH1A1 (0.53) | KMT2AMEN1MAPTMAPK1RXFP1 | |
| SCHEMBL28885886 | 0.74 | KCNH3 (0.53) | KMT2AMEN1MAPTMAPK1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011119704-A1 | TRPV4 ANTAGONISTS | GLAXOSMITHKLINE LLC (US) | 2011-09-29 | — | — | WO | disclosed |