Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | PRKCA | P17252 | 3/20 | 0.32 |
| ▸ | RASGRP3 | Q8IV61 | 3/20 | 0.32 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23716849 | 0.78 | KMT2A (0.36) | NPC1RAB9ASMN1; SMN2MAPTGAA | |
| SCHEMBL10345791 | 0.65 | ALDH1A1 (0.63) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL26424956 | 0.65 | GSTP1 (0.42) | APOBEC3AAPOBEC3GNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11985689 | 0.64 | MAPT (0.73) | APOBEC3AAPOBEC3GNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19214420 | 0.64 | ALDH1A1 (0.61) | APOBEC3AAPOBEC3GNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL26425058 | 0.64 | GSTP1 (0.64) | — | |
| SCHEMBL12532605 | 0.63 | NPC1 (0.67) | APOBEC3AAPOBEC3GNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12201118 | 0.62 | NPC1 (0.54) | APOBEC3AAPOBEC3GNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27824110 | 0.61 | SMN1; SMN2 (0.64) | NPC1RAB9ASMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL24370251 | 0.61 | MAPT (0.56) | APOBEC3AAPOBEC3GNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155253-A1 | ANAT INHIBITORS AND METHODS OF USE THEREOF | Atomwise Inc. (US) | 2021-08-05 | — | — | WO | disclosed |