Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.32 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.31 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.31 |
| ▸ | ITGAL | P20701 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.31 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23716845 | 0.78 | APOBEC3A (0.37) | KMT2ASMN1; SMN2MAPTNPC1RAB9A | |
| SCHEMBL13202360 | 0.62 | KMT2A (0.43) | KMT2AMEN1HTTAGTR1SMN1; SMN2 | |
| SCHEMBL7520602 | 0.61 | KMT2A (0.68) | KMT2AMEN1HTTAGTR1SMN1; SMN2 | |
| SCHEMBL18775878 | 0.60 | KMT2A (0.53) | KMT2AMEN1HTTAGTR1SMN1; SMN2 | |
| SCHEMBL10413526 | 0.60 | SMN1; SMN2 (0.57) | KMT2AMEN1HTTAGTR1SMN1; SMN2 | |
| SCHEMBL11345034 | 0.60 | KMT2A (0.56) | KMT2AMEN1HTTAGTR1SMN1; SMN2 | |
| SCHEMBL4975483 | 0.60 | CYP3A4 (0.57) | KMT2AMEN1HTTAGTR1SMN1; SMN2 | |
| SCHEMBL28350729 | 0.59 | KMT2A (0.77) | KMT2AMEN1HTTAGTR1RAB9A | |
| SCHEMBL11846287 | 0.59 | ALDH1A1 (0.59) | KMT2AMEN1HTTAGTR1SMN1; SMN2 | |
| SCHEMBL18481835 | 0.59 | KMT2A (0.73) | KMT2ATDP1L3MBTL1MAPK1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155253-A1 | ANAT INHIBITORS AND METHODS OF USE THEREOF | Atomwise Inc. (US) | 2021-08-05 | — | — | WO | disclosed |