Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | SOS1 | Q07889 | 6/20 | 0.40 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.32 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23717022 | 0.78 | MAOA (0.55) | ALDH1A1HDAC4HDAC8FYNCYP2C9 | |
| SCHEMBL23717023 | 0.78 | MAOA (0.44) | ALDH1A1SOS1HDAC4HDAC8CYP2C19 | |
| SCHEMBL30632059 | 0.76 | ALDH1A1 (0.54) | ALDH1A1PDE3BPDE3ACYP2C9CYP2C19 | |
| SCHEMBL3143003 | 0.76 | ALDH1A1 (0.54) | ALDH1A1PDE3BPDE3ACYP2C9CYP2C19 | |
| SCHEMBL23717076 | 0.73 | PTGS2 (0.52) | ALDH1A1CYP2C9 | |
| SCHEMBL10283932 | 0.73 | NQO1 (0.47) | ALDH1A1SOS1HDAC4HDAC8 | |
| SCHEMBL10141676 | 0.70 | ALDH1A1 (0.38) | ALDH1A1SOS1CRHR1HDAC4HDAC8 | |
| SCHEMBL26830587 | 0.69 | RXFP1 (0.42) | SOS1CRHR1HDAC4HDAC8POLB | |
| SCHEMBL23717026 | 0.68 | EGFR (0.38) | ALDH1A1CRHR1HDAC4HDAC8FYN | |
| SCHEMBL23717242 | 0.68 | HDAC4 (0.36) | ALDH1A1SOS1CRHR1HDAC4HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230125803-A1 | ANTIVIRAL HETEROCYCLIC COMPOUNDS | ENANTA PHARM INC (US) | 2023-04-27 | — | — | US | disclosed |
| US-20230108803-A1 | ANTIVIRAL HETEROCYCLIC COMPOUNDS | ENANTA PHARMACEUTICALS, INC. | 2023-04-06 | — | — | US | disclosed |
| US-11420976-B2 | Heterocyclic compounds as anti-viral agents | ENANTA PHARMACEUTICALS, INC. (US) | 2022-08-23 | — | — | US | disclosed |
| US-20210238188-A1 | HETEROCYCLIC COMPOUNDS AS ANTI-VIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210238188-A1 | HETEROCYCLIC COMPOUNDS AS ANTI-VIRAL AGENTS | VIP, ACE, FURIN | ALDH1A1 1686/4885SOS1 2746/4885CRHR1 1212/4885 |
| US-11420976-B2 | Heterocyclic compounds as anti-viral agents | VIP, ACE, FURIN | ALDH1A1 1686/4885SOS1 2746/4885CRHR1 1212/4885 |
| US-20230108803-A1 | ANTIVIRAL HETEROCYCLIC COMPOUNDS | ACE, HPRT1, ACE2 | ALDH1A1 2176/4885SOS1 1860/4885CRHR1 1173/4885 |
| US-20230125803-A1 | ANTIVIRAL HETEROCYCLIC COMPOUNDS | ACE, HPRT1, ACE2 | ALDH1A1 2176/4885SOS1 1860/4885CRHR1 1173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.