Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.56 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.56 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.56 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.53 |
| ▸ | MKNK1 | Q9BUB5 | 4/20 | 0.50 |
| ▸ | MKNK2 | Q9HBH9 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ABL1 | P00519 | 2/20 | 0.48 |
| ▸ | BCR | P11274 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 1/20 | 0.48 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 2/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23685090 | 0.86 | KMO (0.52) | CYP11B1CYP11B2CYP19A1MKNK1MKNK2 | |
| SCHEMBL20021946 | 0.81 | PDE4D (0.54) | ALDH1A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24986894 | 0.81 | ABL1 (0.42) | ALDH1A1ABL1PDE4APDE4BPDE4C | |
| SCHEMBL18355729 | 0.80 | MKNK1 (0.76) | CYP11B1CYP11B2CYP19A1SLC2A1MKNK1 | |
| SCHEMBL7084334 | 0.77 | CYP11B1 (0.64) | CYP11B1CYP11B2CYP19A1SLC2A1MKNK1 | |
| SCHEMBL23717048 | 0.77 | CYP11B1 (0.47) | CYP11B1CYP11B2CYP19A1MKNK1MKNK2 | |
| SCHEMBL18031253 | 0.76 | MAPT (0.53) | PDE4APDE4BPDE4CPDE4DKMT2A | |
| SCHEMBL20021952 | 0.76 | PDE4A (0.64) | ALDH1A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL20021950 | 0.74 | SLC6A3 (0.50) | ALDH1A1PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL30710434 | 0.74 | CYP11B1 (0.54) | CYP11B1CYP11B2CYP19A1SLC2A1MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021150806-A1 | HETEROCYCLIC COMPOUNDS AS ANTI-VIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. (US) | 2021-07-29 | — | — | WO | disclosed |