Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.33 |
| ▸ | ADH1C | P00326 | 1/20 | 0.33 |
| ▸ | ADH1A | P07327 | 1/20 | 0.33 |
| ▸ | ADH4 | P08319 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.33 |
| ▸ | MAOA | P21397 | 4/20 | 0.33 |
| ▸ | MAOB | P27338 | 4/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1932588 | 0.81 | L3MBTL1 (0.41) | L3MBTL1ALDH1A1LMNAPTBP1ADH1C | |
| SCHEMBL5510945 | 0.80 | L3MBTL1 (0.42) | L3MBTL1ADH1CADH1A | |
| SCHEMBL13275824 | 0.79 | SMN1; SMN2 (0.34) | SMN1; SMN2GAA | |
| SCHEMBL13275823 | 0.79 | SMN1; SMN2 (0.34) | SMN1; SMN2GAA | |
| SCHEMBL3818321 | 0.78 | SLC6A4 (0.44) | L3MBTL1 | |
| Hydrochloric Acid SCHEMBL27341644 | 0.78 | L3MBTL1 (0.43) | L3MBTL1ALDH1A1LMNAPTBP1ADH1C | |
| SCHEMBL16055381 | 0.77 | SLC6A4 (0.40) | L3MBTL1ADH1CADH1AADH4OPRM1 | |
| SCHEMBL5027243 | 0.75 | L3MBTL1 (0.39) | L3MBTL1ALDH1A1LMNAPTBP1TRPM8 | |
| SCHEMBL18074732 | 0.75 | ALDH1A1 (0.43) | L3MBTL1SMN1; SMN2BCHEALDH1A1LMNA | |
| SCHEMBL9938924 | 0.75 | ADH1C (0.38) | L3MBTL1ALDH1A1LMNAPTBP1ADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2545037-A1 | INHIBITORS OF PROTEIN KINASES | Ingenium Pharmaceuticals GmbH (DE) | 2013-01-16 | — | — | EP | disclosed |
| WO-2011110612-A1 | INHIBITORS OF PROTEIN KINASES | INGENIUM PHARMACEUTICALS GMBH (DE) | 2011-09-15 | — | — | WO | disclosed |