Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.42 |
| ▸ | PDE2A | O00408 | 1/20 | 0.42 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4411993 | 0.79 | MAOA (0.60) | MAOAPDE10AALDH1A1CYP3A4MAPK1 | |
| SCHEMBL19663000 | 0.79 | MAOA (0.40) | MAOAALDH1A1SMN1; SMN2ACHERAB9A | |
| SCHEMBL29831723 | 0.79 | MAOA (0.60) | MAOAPDE10AALDH1A1CYP3A4MAPK1 | |
| SCHEMBL11176425 | 0.78 | MAOA (0.58) | MAOAALDH1A1CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL23166970 | 0.78 | MAOA (0.58) | MAOAPDE10ALMNAUSP2ALDH1A1 | |
| SCHEMBL29923831 | 0.78 | MAOA (0.39) | MAOAALDH1A1SMN1; SMN2ACHECREBBP | |
| SCHEMBL23717076 | 0.77 | PTGS2 (0.52) | PTGS2PDE10AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL24510994 | 0.77 | PTGS2 (0.52) | PTGS2PDE10ALMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL21237375 | 0.75 | HSPA5 (0.39) | MAOAALDH1A1SMN1; SMN2RAB9ACREBBP | |
| SCHEMBL23717022 | 0.75 | MAOA (0.55) | MAOAALDH1A1CYP3A4MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11420976-B2 | Heterocyclic compounds as anti-viral agents | ENANTA PHARMACEUTICALS, INC. (US) | 2022-08-23 | — | — | US | disclosed |
| US-20210238188-A1 | HETEROCYCLIC COMPOUNDS AS ANTI-VIRAL AGENTS | ENANTA PHARMACEUTICALS, INC. | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210238188-A1 | HETEROCYCLIC COMPOUNDS AS ANTI-VIRAL AGENTS | VIP, ACE, FURIN | MAOA 2105/4885PTGS2 400/4885PDE10A 2051/4885 |
| US-11420976-B2 | Heterocyclic compounds as anti-viral agents | VIP, ACE, FURIN | MAOA 2105/4885PTGS2 400/4885PDE10A 2051/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.