Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | MC5R | P33032 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | MC1R | Q01726 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22041221 | 0.86 | MC5R (0.50) | HPGDMC5RMAPK1MC1RMEN1 | |
| SCHEMBL6008064 | 0.85 | MC5R (0.70) | HPGDMC5RMAPK1MC1RMEN1 | |
| SCHEMBL15131007 | 0.78 | MAPK1 (0.67) | HPGDMC5RMAPK1MC1RMEN1 | |
| SCHEMBL20495649 | 0.77 | HPGD (0.69) | HPGDMC5RMAPK1MC1RMEN1 | |
| SCHEMBL29582547 | 0.77 | HPGD (0.69) | HPGDMC5RMAPK1MC1RMEN1 | |
| SCHEMBL2865597 | 0.77 | MC5R (0.70) | HPGDMC5RMAPK1MC1RMEN1 | |
| SCHEMBL30482193 | 0.77 | MC5R (0.70) | HPGDMC5RMAPK1MC1RMEN1 | |
| SCHEMBL9305839 | 0.75 | MC5R (0.58) | HPGDMC5RMAPK1MC1RMEN1 | |
| SCHEMBL3626833 | 0.74 | MC5R (0.57) | HPGDMC5RMAPK1MC1RMEN1 | |
| SCHEMBL21379748 | 0.73 | HPGD (0.63) | HPGDMC5RMAPK1MC1RCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11078164-B1 | PTEN binding compounds, formulations, and uses thereof | UNIVERSITY OF SOUTH FLORIDA (US) | 2021-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11078164-B1 | PTEN binding compounds, formulations, and uses thereof | PTEN, EYA2, PIK3CA | HPGD 3404/4885MC5R 3992/4885MAPK1 1516/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.