SCHEMBL23718039

SCHEMBL23718039

CCN(CC)CCCC[C@H](NC(=O)[C@@H](CC(C)C)NC(=O)[C@H](N)NC(=O)[C@H](Cc1ccccc1)NC(=O)c1ccc(C(C)(C)C)cc1)C(=O)N[C@@H](CO)C(=O)OC

nearest known ligand 0.75

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CDYL2 Q8N8U2 6/20 0.75
CBX7 O95931 4/20 0.75
CBX8 Q9HC52 4/20 0.75
CBX4 O00257 3/20 0.75
CBX6 O95503 1/20 0.64
CBX2 Q14781 1/20 0.64
KISS1R Q969F8 1/20 0.43
OPRK1 P41145 4/20 0.42
NPY4R P50391 2/20 0.42
OPRM1 P35372 2/20 0.42
NPY1R P25929 1/20 0.42
GAA P10253 1/20 0.41
RAB9A P51151 1/20 0.41
CTSG P08311 1/20 0.40
CMA1 P23946 1/20 0.40
PSMB5 P28074 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23815796 1.00 CDYL2 (0.75) CDYL2CBX7CBX8CBX4CBX6
SCHEMBL23682719 0.93 CDYL2 (0.87) CDYL2CBX7CBX8CBX4CBX6
SCHEMBL26219950 0.93 CDYL2 (0.87) CDYL2CBX7CBX8CBX4CBX6
SCHEMBL23717921 0.93 CDYL2 (0.87) CDYL2CBX7CBX8CBX4CBX6
SCHEMBL23682865 0.93 CDYL2 (0.87) CDYL2CBX7CBX8CBX4CBX6
SCHEMBL23718040 0.93 CDYL2 (0.87) CDYL2CBX7CBX8CBX4CBX6
SCHEMBL25049665 0.90 CDYL2 (0.72) CDYL2CBX7CBX8CBX4CBX6
SCHEMBL23815823 0.90 CDYL2 (0.72) CDYL2CBX7CBX8CBX4CBX6
SCHEMBL23682687 0.90 CDYL2 (0.72) CDYL2CBX7CBX8CBX4CBX6
SCHEMBL23815561 0.86 CDYL2 (0.78) CDYL2CBX7CBX8CBX4CBX6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230050819-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE Design Therapeutics, Inc. 2023-02-16 US disclosed
US-20210238226-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE Design Therapeutics, Inc. 2021-08-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210238226-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE ATXN2L, ATXN2, ATXN10 CDYL2 1804/4885CBX7 1030/4885CBX8 1268/4885
US-20230050819-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE CYFIP2, TPX2, ATXN2 CDYL2 251/4885CBX7 300/4885CBX8 169/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.