Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 2/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24370508 | 0.85 | CNR2 (0.41) | CNR2NFE2L2CYP3A4ATMTYR | |
| SCHEMBL18488343 | 0.78 | TYR (0.47) | TYRALDH1A1TSHRKDM4ERAB9A | |
| SCHEMBL29956336 | 0.78 | TYR (0.47) | TYRALDH1A1TSHRKDM4ERAB9A | |
| SCHEMBL18488113 | 0.78 | NFE2L2 (0.33) | NFE2L2 | |
| SCHEMBL18488056 | 0.78 | ALDH1A1 (0.39) | NFE2L2ALDH1A1MAPTLMNATP53 | |
| SCHEMBL7655780 | 0.77 | NFE2L2 (0.63) | CNR2NFE2L2CYP3A4ATMTYR | |
| SCHEMBL7654214 | 0.77 | NFE2L2 (0.63) | CNR2NFE2L2CYP3A4ATMTYR | |
| SCHEMBL7654210 | 0.77 | NFE2L2 (0.63) | CNR2NFE2L2CYP3A4ATMTYR | |
| SCHEMBL16953105 | 0.74 | NFE2L2 (0.48) | CNR2NFE2L2CYP3A4ATMTYR | |
| SCHEMBL10624527 | 0.74 | TUBB1 (0.49) | CNR2NFE2L2CYP3A4ATMTYR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2892534-B1 | COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | PLEXXIKON INC (US) | 2021-08-04 | — | — | EP | disclosed |