Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4885292 | 0.84 | EPHX1 (0.46) | EPHX1TRPM8TRPA1CYP19A1ALDH1A1 | |
| SCHEMBL9996875 | 0.83 | EPHX1 (0.45) | EPHX1TRPM8TRPA1CYP19A1ALDH1A1 | |
| SCHEMBL457824 | 0.80 | EPHX1 (0.51) | EPHX1TRPM8TRPA1CYP19A1TRPV1 | |
| SCHEMBL9951381 | 0.80 | EPHX1 (0.51) | EPHX1TRPM8TRPA1CYP19A1ALDH1A1 | |
| SCHEMBL9951688 | 0.80 | EPHX1 (0.51) | EPHX1TRPM8TRPA1CYP19A1ALDH1A1 | |
| SCHEMBL9951572 | 0.80 | EPHX1 (0.51) | EPHX1TRPM8TRPA1CYP19A1TRPV1 | |
| SCHEMBL28350744 | 0.80 | EPHX1 (0.51) | EPHX1TRPM8TRPA1CYP19A1ALDH1A1 | |
| SCHEMBL10028627 | 0.78 | EPHX1 (0.59) | EPHX1TRPM8TRPA1CYP19A1ALDH1A1 | |
| SCHEMBL20058320 | 0.77 | P2RX4 (0.52) | EPHX1CYP19A1ALDH1A1USP2LMNA | |
| SCHEMBL16304051 | 0.77 | P2RX4 (0.52) | EPHX1CYP19A1ALDH1A1USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3445743-B1 | PRODRUG OF AMINO ACID DERIVATIVE | TAISHO PHARMACEUTICAL CO LTD (JP) | 2021-08-04 | — | — | EP | disclosed |