SCHEMBL10028627

SCHEMBL10028627

CC1CCC(C(C)C)C(CC(N)=O)C1

nearest known ligand 0.59

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 3/20 0.59
TRPM8 Q7Z2W7 4/20 0.48
TRPA1 O75762 2/20 0.48
ALDH1A1 P00352 3/20 0.39
HPGD P15428 1/20 0.39
TRPV1 Q8NER1 3/20 0.38
CYP19A1 P11511 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9951381 0.84 EPHX1 (0.51) EPHX1TRPM8TRPA1ALDH1A1TRPV1
SCHEMBL28350744 0.84 EPHX1 (0.51) EPHX1TRPM8TRPA1ALDH1A1HPGD
SCHEMBL9951688 0.84 EPHX1 (0.51) EPHX1TRPM8TRPA1ALDH1A1TRPV1
SCHEMBL457824 0.84 EPHX1 (0.51) EPHX1TRPM8TRPA1TRPV1CYP19A1
SCHEMBL9951572 0.84 EPHX1 (0.51) EPHX1TRPM8TRPA1TRPV1CYP19A1
Acetic Acid SCHEMBL30541669 0.81 EPHX1 (0.49) EPHX1TRPM8TRPA1TRPV1CYP19A1
Formaldehyde SCHEMBL31298519 0.81 EPHX1 (0.49) EPHX1TRPM8TRPA1TRPV1CYP19A1
SCHEMBL11291061 0.81 EPHX1 (0.49) EPHX1TRPM8TRPA1ALDH1A1TRPV1
SCHEMBL3793761 0.79 EPHX1 (0.47) EPHX1TRPM8TRPA1TRPV1
SCHEMBL23718853 0.78 EPHX1 (0.46) EPHX1TRPM8TRPA1ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 294 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107954824-B Method for synthesizing menthane carboxamide by using menthol 昆山亚香香料股份有限公司 2022-12-27 CN claimed
EP-4103287-A1 COMPOSITIONS COMPRISING (BIO)-ALKANEDIOLS AND COOLING AGENTS Symrise AG (DE) 2022-12-21 EP claimed
WO-2022122903-A1 COMPOSITIONS COMPRISING (BIO)-ALKANEDIOLS AND COOLING AGENTS SYMRISE AG (DE) 2022-06-16 WO claimed
WO-2022122134-A1 COMPOSITIONS WITH (BIO)-ALKANEDIOLS AND COOLING AGENTS SYMRISE AG (DE) 2022-06-16 WO claimed
EP-4734939-A2 ORAL CARE COMPOSITIONS COMPRISING HOPS BETA ACIDS The Procter & Gamble Company (US) 2026-05-06 EP disclosed
EP-4734922-A2 ORAL CARE COMPOSITIONS COMPRISING HOPS BETA ACIDS AND TIN The Procter & Gamble Company (US) 2026-05-06 EP disclosed
EP-4447907-B1 ORAL CARE COMPOSITION COMPRISING PHYTATES AND PIGMENT UNILEVER IP HOLDINGS B V (NL) 2026-04-22 EP disclosed
US-20260102322-A1 ORAL CARE COMPOSITIONS COMPRISING CARBOXYLIC ACIDS PROCTER & GAMBLE (US) 2026-04-16 US disclosed
US-20260083649-A1 ORAL CARE COMPOSITIONS COMPRISING MINT OIL AND TIN PROCTER & GAMBLE (US) 2026-03-26 US disclosed
US-20260076894-A1 ORAL CARE COMPOSITIONS COMPRISING HOPS AND TIN PROCTER & GAMBLE (US) 2026-03-19 US disclosed
US-12551414-B2 Systems and methods for delivering active agents THE PROCTER & GAMBLE COMPANY (US) 2026-02-17 US disclosed
EP-4133047-B1 CLEANING ARTICLE WITH PREFERENTIAL RHEOLOGICAL SOLID COMPOSITION PROCTER & GAMBLE (US) 2026-02-11 EP disclosed
EP-3373895-A1 REDUCTION OF STINGING SENSATION ON SKIN Symrise AG (DE) 2018-09-19 EP disclosed
US-20180185301-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POLYALKYLENE GLYCOL DERIVATIVES SYMRISE AG (DE) 2018-07-05 US disclosed
WO-2017080625-A1 REDUCTION OF STINGING SENSATION ON SKIN SYMRISE AG (DE) 2017-05-18 WO disclosed
EP-3081207-A1 WHITENING COMPOSITIONS Symrise AG (DE) 2016-10-19 EP disclosed
WO-2014198366-A1 GLOVE WITH A COOLING EFFECT CARL FREUDENBERG KG (DE) 2014-12-18 WO disclosed
US-20120165559-A1 Compounds Having a Physiological Effect V. MANE FILS (FR) 2012-06-28 US disclosed
US-20120165559-A1 Compounds Having a Physiological Effect V. MANE FILS (FR) 2012-06-28 US disclosed
WO-2010122239-A1 COMPOUNDS HAVING A PHYSIOLOGICAL EFFECT V. MANE FILS (FR) 2010-10-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260083649-A1 ORAL CARE COMPOSITIONS COMPRISING MINT OIL AND TIN TAS2R40, SOD1, TAS2R10 EPHX1 4819/4885TRPM8 123/4885TRPA1 416/4885
US-20260102322-A1 ORAL CARE COMPOSITIONS COMPRISING CARBOXYLIC ACIDS OTC, ODC1, SDC1 EPHX1 4323/4885TRPM8 1265/4885TRPA1 2330/4885
US-20260076894-A1 ORAL CARE COMPOSITIONS COMPRISING HOPS AND TIN SOD1, SOD3, HMBS EPHX1 4797/4885TRPM8 236/4885TRPA1 435/4885
US-12551414-B2 Systems and methods for delivering active agents CRYZ, CRY2, SMARCA1 EPHX1 1634/4885TRPM8 3428/4885TRPA1 2723/4885
US-20180185301-A1 PHARMACEUTICAL COMPOSITIONS COMPRISING POLYALKYLENE GLYCOL DERIVATIVES PARG, PARN, TRPV1 EPHX1 1542/4885TRPM8 199/4885TRPA1 74/4885
US-20120165559-A1 Compounds Having a Physiological Effect NPPA, CYP11B2, SHBG EPHX1 871/4885TRPM8 412/4885TRPA1 418/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.