Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.51 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | USP7 | Q93009 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.44 |
| ▸ | TACR1 | P25103 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23718995 | 0.88 | NPC1 (0.60) | OPRM1OPRL1OPRD1OPRK1NPC1 | |
| SCHEMBL23719017 | 0.87 | OPRM1 (0.56) | OPRM1OPRL1OPRD1OPRK1MEN1 | |
| SCHEMBL23719011 | 0.82 | EPHX2 (0.53) | OPRM1OPRL1OPRD1OPRK1MEN1 | |
| SCHEMBL23719100 | 0.81 | GFER (0.59) | OPRM1OPRL1OPRD1OPRK1MEN1 | |
| SCHEMBL13733764 | 0.78 | OPRM1 (0.62) | OPRM1OPRL1OPRK1 | |
| SCHEMBL2469668 | 0.78 | PLAAT3 (0.54) | OPRM1OPRD1MEN1KMT2AMAPT | |
| SCHEMBL10254031 | 0.78 | NAAA (0.48) | OPRD1OPRK1MEN1KMT2AMAPT | |
| SCHEMBL17444449 | 0.77 | OPRM1 (0.79) | OPRM1OPRL1OPRD1OPRK1NPC1 | |
| SCHEMBL17444448 | 0.77 | OPRM1 (0.79) | OPRM1OPRL1OPRD1OPRK1NPC1 | |
| Hydrochloric Acid SCHEMBL3401730 | 0.77 | OPRM1 (0.60) | OPRM1OPRL1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858439-A1 | AMIDE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2021-08-04 | — | — | EP | disclosed |