SCHEMBL2371933

SCHEMBL2371933

[CH2]NS(=O)(=O)c1ccccc1Cl

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.53
GAA P10253 1/20 0.53
TSHR P16473 1/20 0.53
HSD17B10 Q99714 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
PGR P06401 1/20 0.49
PKM P14618 1/20 0.47
POLB P06746 1/20 0.46
SLC1A3 P43003 1/20 0.46
SLC1A2 P43004 1/20 0.46
SLC1A1 P43005 1/20 0.46
FLT1 P17948 1/20 0.46
FLT4 P35916 1/20 0.46
KDR P35968 1/20 0.46
SLC22A12 Q96S37 2/20 0.45
EDNRA P25101 2/20 0.45
MCL1 Q07820 1/20 0.45
SLC40A1 Q9NP59 1/20 0.44
EDNRB P24530 1/20 0.43
HSD11B1 P28845 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2372744 0.83 PTGES2 (0.54) TSHRPGRSLC40A1
SCHEMBL6928314 0.82 ALDH1A1 (0.56) ALDH1A1GAATSHRHSD17B10L3MBTL1
SCHEMBL5806023 0.80 ALDH1A1 (0.55) ALDH1A1GAATSHRHSD17B10L3MBTL1
SCHEMBL9598797 0.78 ALDH1A1 (0.53) ALDH1A1GAATSHRHSD17B10L3MBTL1
SCHEMBL1767992 0.78 CA1 (0.55) ALDH1A1GAATSHRHSD17B10L3MBTL1
SCHEMBL23747022 0.78 ALDH1A1 (0.53) ALDH1A1GAATSHRHSD17B10L3MBTL1
Potassium SCHEMBL9789251 0.78 ALDH1A1 (0.53) ALDH1A1GAATSHRHSD17B10L3MBTL1
SCHEMBL2371935 0.78 GAA (0.58) ALDH1A1GAATSHRHSD17B10L3MBTL1
SCHEMBL2244891 0.78 ALDH1A1 (0.53) ALDH1A1GAATSHRHSD17B10L3MBTL1
SCHEMBL420397 0.78 GAA (0.53) ALDH1A1GAATSHRHSD17B10L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2547204-A2 ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS Bayer Intellectual Property GmbH (DE) 2013-01-23 EP claimed
US-20110230350-A1 ARYL-AND HETARYLSULFONAMIDES AS ACTIVE INGREDIENTS AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2011-09-22 US claimed
WO-2011113861-A2 ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2011-09-22 WO claimed
EP-2547204-A2 ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS Bayer Intellectual Property GmbH (DE) 2013-01-23 EP disclosed
US-20110230350-A1 ARYL-AND HETARYLSULFONAMIDES AS ACTIVE INGREDIENTS AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2011-09-22 US disclosed
WO-2011113861-A2 ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2011-09-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110230350-A1 ARYL-AND HETARYLSULFONAMIDES AS ACTIVE INGREDIENTS AGAINST ABIOTIC PLANT STRESS STS, ARSA, TST ALDH1A1 1980/4885GAA 218/4885TSHR 3315/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.