Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | EDNRA | P25101 | 2/20 | 0.49 |
| ▸ | PGR | P06401 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4731653 | 0.84 | CYP1A2 (0.55) | GAATSHRALDH1A1L3MBTL1CYP1A2 | |
| SCHEMBL2372746 | 0.83 | PTGES2 (0.54) | TSHRPGRPTGES2 | |
| SCHEMBL6928314 | 0.82 | ALDH1A1 (0.56) | GAATSHRHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL16002844 | 0.80 | PTGES2 (0.56) | ALDH1A1CA12CA1CA2CA3 | |
| SCHEMBL6074022 | 0.80 | CYP3A4 (0.59) | TSHRHSD17B10ALDH1A1EDNRACYP1A2 | |
| SCHEMBL5806023 | 0.80 | ALDH1A1 (0.55) | GAATSHRHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL3583413 | 0.79 | NSD2 (0.50) | GAATSHRHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL23747022 | 0.78 | ALDH1A1 (0.53) | GAATSHRHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL10855740 | 0.78 | CYP1A2 (0.47) | GAATSHRHSD17B10ALDH1A1L3MBTL1 | |
| SCHEMBL1767992 | 0.78 | CA1 (0.55) | GAATSHRHSD17B10ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2547204-A2 | ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS | Bayer Intellectual Property GmbH (DE) | 2013-01-23 | — | — | EP | claimed |
| US-20110230350-A1 | ARYL-AND HETARYLSULFONAMIDES AS ACTIVE INGREDIENTS AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2011-09-22 | — | — | US | claimed |
| WO-2011113861-A2 | ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2011-09-22 | — | — | WO | claimed |
| EP-4661966-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS OF USE THEREOF | Type6 Therapeutics, Inc. (US) | 2025-12-17 | — | — | EP | disclosed |
| US-12479818-B2 | Treatment of fibrosis with IRE1 small molecule inhibitors | CORNELL UNIVERSITY (US) | 2025-11-25 | — | — | US | disclosed |
| WO-2024167848-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS OF USE THEREOF | TYPE6 THERAPEUTICS, INC. (US) | 2024-08-15 | — | — | WO | disclosed |
| EP-3891130-B1 | IRE1 SMALL MOLECULE INHIBITORS | UNIV CORNELL (US) | 2023-10-25 | — | — | EP | disclosed |
| EP-3483143-B1 | PIPERIDINONE DERIVATIVES AS MDM2 INHIBITORS FOR THE TREATMENT OF CANCER | AMGEN INC (US) | 2023-10-18 | — | — | EP | disclosed |
| WO-2023177877-A1 | RALINEPAG PRODRUGS AND USES THEREOF | UNITED THERAPEUTICS CORPORATION (US) | 2023-09-21 | — | — | WO | disclosed |
| EP-3675858-B1 | IMIDAZO[1,5-A]PYRAZINE COMPOUNDS AND COMPOSITIONS FOR IRE1 INHIBITION | OPTIKIRA LLC (US) | 2023-04-26 | — | — | EP | disclosed |
| US-20220227730-A1 | TREATMENT OF FIBROSIS WITH IRE1 SMALL MOLECULE INHIBITORS | CORNELL UNIVERSITY | 2022-07-21 | — | — | US | disclosed |
| US-20040063725-A1 | Novel n(phenylsulphonyl)glycine derivatives and their therapeutic use | LABORATORIES FOURNIER S.A. (FR) | 2004-04-01 | — | — | US | disclosed |
| CN-1484633-A | N (phenylsulphonyl) glycine derivatives and their therapentic use | ʵ���Ҹ���Ү��˾ | 2004-03-24 | — | — | CN | disclosed |
| WO-2003106428-A1 | NOVEL ARYLSULPHONAMIDE DERIVATIVES AND USE THEREOF AS THERAPEUTIC AGENTS | LABORATOIRES FOURNIER SA (FR) | 2003-12-24 | — | — | WO | disclosed |
| EP-1351928-A2 | NOVEL N(PHENYLSULPHONYL)GLYCINE DERIVATIVES AND THEIR THERAPEUTIC USE | LABORATOIRES FOURNIER S.A. (FR) | 2003-10-15 | — | — | EP | disclosed |
| WO-2002053516-A2 | N(PHENYLSULPHONYL)GLYCINE DERIVATIVES AND THEIR THERAPEUTIC USE | LABORATOIRES FOURNIER SA (FR) | 2002-07-11 | — | — | WO | disclosed |
| EP-0135332-B1 | HERBICIDAL BENZENESULFONAMIDES, BENZYLSULFONAMIDES AND BENZENESULFAMATES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-12-07 | — | — | EP | disclosed |
| US-4786316-A | PRE-AND POST-EMERGENT HERBICIDES, PLANT GROWTH REGULATOR | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1988-11-22 | — | — | US | disclosed |
| US-4652304-A | Herbicidal ortho-sulfamoyl sulfonamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-03-24 | — | — | US | disclosed |
| EP-0135332-A1 | Herbicidal benzenesulfonamides, benzylsulfonamides and benzenesulfamates | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-03-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220227730-A1 | TREATMENT OF FIBROSIS WITH IRE1 SMALL MOLECULE INHIBITORS | XBP1, DDIT3, ATF4 | GAA 2449/4885TSHR 4260/4885HSD17B10 1717/4885 |
| US-20110230350-A1 | ARYL-AND HETARYLSULFONAMIDES AS ACTIVE INGREDIENTS AGAINST ABIOTIC PLANT STRESS | STS, ARSA, TST | GAA 218/4885TSHR 3315/4885HSD17B10 543/4885 |
| US-12479818-B2 | Treatment of fibrosis with IRE1 small molecule inhibitors | XBP1, DDIT3, HSP90B1 | GAA 2332/4885TSHR 4348/4885HSD17B10 1625/4885 |
| US-20040063725-A1 | Novel n(phenylsulphonyl)glycine derivatives and their therapeutic use | GLS, GLS2, GLRB | GAA 492/4885TSHR 2289/4885HSD17B10 3810/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.