Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.36 |
| ▸ | ACP1 | P24666 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12957927 | 0.85 | L3MBTL1 (0.46) | L3MBTL1HPGDMAPTALDH1A1MEN1 | |
| SCHEMBL19501726 | 0.80 | CNR2 (0.46) | L3MBTL1HPGDMAPTALDH1A1MEN1 | |
| SCHEMBL19862827 | 0.78 | L3MBTL1 (0.54) | L3MBTL1HPGDMAPTALDH1A1MEN1 | |
| SCHEMBL25878006 | 0.78 | L3MBTL1 (0.54) | L3MBTL1HPGDMAPTALDH1A1MEN1 | |
| SCHEMBL19735249 | 0.78 | L3MBTL1 (0.54) | L3MBTL1HPGDMAPTALDH1A1MEN1 | |
| SCHEMBL20821376 | 0.77 | L3MBTL1 (0.48) | L3MBTL1HPGDMAPTALDH1A1MEN1 | |
| SCHEMBL19558571 | 0.75 | CNR2 (0.48) | L3MBTL1HPGDMAPTALDH1A1MEN1 | |
| SCHEMBL23680532 | 0.75 | L3MBTL1 (0.50) | L3MBTL1HPGDMAPTALDH1A1MEN1 | |
| SCHEMBL25817366 | 0.74 | L3MBTL1 (0.48) | L3MBTL1HPGDMAPTALDH1A1MEN1 | |
| SCHEMBL25817457 | 0.74 | L3MBTL1 (0.48) | L3MBTL1HPGDMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11081650-B2 | Spiro compound and organic light-emitting element comprising same | LG CHEM, LTD. | 2021-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11081650-B2 | Spiro compound and organic light-emitting element comprising same | RER1, NR2E3, RIF1 | L3MBTL1 1222/4885HPGD 3893/4885MAPT 2533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.