SCHEMBL23720035

SCHEMBL23720035

Nc1nc2ccc(Sc3cccnc3Cl)cc2s1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PI4KA P42356 8/20 0.51
PI4KB Q9UBF8 8/20 0.51
PIK3CD O00329 7/20 0.51
PIK3CG P48736 6/20 0.51
PIK3CA P42336 6/20 0.51
PIP5K1C O60331 4/20 0.51
KCNH2 Q12809 1/20 0.50
CYP3A4 P08684 2/20 0.49
CYP1A2 P05177 1/20 0.48
AXL P30530 1/20 0.47
GFER P55789 1/20 0.47
PIK3CB P42338 4/20 0.46
RAB9A P51151 3/20 0.43
MAPT P10636 2/20 0.43
HTT P42858 2/20 0.43
GAA P10253 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
CYP2C9 P11712 1/20 0.42
TP53 P04637 3/20 0.41
ALDH1A1 P00352 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31683905 1.00 PI4KA (0.51) PI4KAPI4KBPIK3CDPIK3CGPIK3CA
SCHEMBL21186214 0.82 CYP3A4 (0.56) PI4KAPI4KBPIK3CDPIK3CGPIK3CA
SCHEMBL25500901 0.81 RAB9A (0.50) PI4KAPI4KBPIK3CDPIK3CGPIK3CA
SCHEMBL5533752 0.78 KCNH2 (0.70) PI4KAPI4KBPIK3CDPIK3CGPIK3CA
SCHEMBL7284884 0.74 CYP3A4 (0.67) PI4KAPI4KBPIK3CDPIK3CGPIK3CA
SCHEMBL23720039 0.74 CYP3A4 (0.54) PI4KAPI4KBPIK3CDPIK3CGPIK3CA
SCHEMBL23720001 0.74 PDE7A (0.49) CYP3A4CYP1A2MAPTL3MBTL1CYP2C9
SCHEMBL1913966 0.70 KCNH2 (0.64) PI4KAPI4KBPIK3CDPIK3CGPIK3CA
SCHEMBL9379829 0.70 CYP3A4 (0.68) PI4KAPI4KBPIK3CDPIK3CGPIK3CA
SCHEMBL1828986 0.69 PI4KA (0.46) PI4KAPI4KBPIK3CDPIK3CGPIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4097111-B9 PYRIDO[2,3-E]OXAZINE DERIVATIVES AS AGRICULTURAL CHEMICALS GLOBACHEM NV (BE) 2025-10-29 EP disclosed
EP-4097111-B1 PYRIDO[2,3-E]OXAZINE DERIVATIVES AS AGRICULTURAL CHEMICALS GLOBACHEM NV (BE) 2025-07-23 EP disclosed
US-20230151023-A1 PYRIDO[2,3-E]OXAZINE DERIVATIVES AS AGRICULTURAL CHEMICALS GLOBACHEM NV (BE) 2023-05-18 US disclosed
US-20230151023-A1 PYRIDO[2,3-E]OXAZINE DERIVATIVES AS AGRICULTURAL CHEMICALS GLOBACHEM NV (BE) 2023-05-18 US disclosed
WO-2021151919-A1 PYRIDO[2,3-E]OXAZINE DERIVATIVES AS AGRICULTURAL CHEMICALS GLOBACHEM NV (BE) 2021-08-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230151023-A1 PYRIDO[2,3-E]OXAZINE DERIVATIVES AS AGRICULTURAL CHEMICALS PNPO, HPD, PDXK PI4KA 870/4885PI4KB 1799/4885PIK3CD 1719/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.