Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 15/20 | 0.44 |
| ▸ | MAOA | P21397 | 13/20 | 0.44 |
| ▸ | MAOB | P27338 | 13/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.36 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.36 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.36 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.36 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23720200 | 1.00 | KDM1A (0.44) | KDM1AMAOAMAOBGAAMCOLN3 | |
| SCHEMBL23720118 | 1.00 | KDM1A (0.44) | KDM1AMAOAMAOBGAAMCOLN3 | |
| SCHEMBL22026800 | 0.67 | GAA (0.52) | GAAMCOLN3ALDH1A1RAB9AKMT2A | |
| SCHEMBL11054309 | 0.66 | KDM1A (0.57) | KDM1AMAOAMAOB | |
| SCHEMBL10573931 | 0.66 | KDM1A (0.57) | KDM1AMAOAMAOB | |
| SCHEMBL10573928 | 0.66 | KDM1A (0.57) | KDM1AMAOAMAOB | |
| SCHEMBL22623894 | 0.65 | GAA (0.38) | GAAMCOLN3ALDH1A1KMT2APSEN1 | |
| SCHEMBL5998298 | 0.65 | KDM1A (0.57) | KDM1AMAOAMAOBRCOR1 | |
| SCHEMBL16865181 | 0.64 | GAA (0.48) | GAAMCOLN3ALDH1A1KMT2A | |
| SCHEMBL27539024 | 0.64 | KDM1A (0.45) | KDM1AMAOAMAOBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210238133-A1 | CYCLOPROPANATION METHOD | OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) | 2021-08-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210238133-A1 | CYCLOPROPANATION METHOD | ADH1A, ADH1C, ADH5 | KDM1A 3468/4885MAOA 708/4885MAOB 457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.