Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18596028 | 0.77 | ALDH1A1 (0.44) | LMNAMAPK1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL18930369 | 0.75 | TRPA1 (0.43) | LMNAMAPK1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL18930354 | 0.73 | TRPA1 (0.41) | LMNAMAPK1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL9979294 | 0.71 | MAPT (0.52) | LMNAMAPTHPGDL3MBTL1TRPA1 | |
| SCHEMBL12190515 | 0.70 | ALDH1A1 (0.52) | LMNAMAPK1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL21023213 | 0.67 | LMNA (0.48) | LMNAMAPK1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL25497035 | 0.67 | MAPK1 (0.50) | LMNAMAPK1MAPTTRPA1PTGS1 | |
| SCHEMBL25494287 | 0.67 | TP53 (0.44) | LMNAMAPK1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL21565742 | 0.65 | LMNA (0.42) | LMNAMAPK1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL25494271 | 0.65 | MEN1 (0.45) | LMNAMAPK1SMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021152623-A1 | IMPROVED PROCESSES FOR THE PREPARATION OF TAFAMIDIS AND ITS MEGLUMINE SALT | DR. REDDY’S LABORATORIES LIMITED (IN) | 2021-08-05 | — | — | WO | disclosed |