Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.51 |
| ▸ | CNR2 | P34972 | 11/20 | 0.50 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 3/20 | 0.44 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.43 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22273415 | 0.86 | KLKB1 (0.49) | LTA4HCNR2KMT2ACA12CA1 | |
| SCHEMBL1581655 | 0.86 | LTA4H (0.55) | LTA4HCNR2NR5A1KMT2ACA12 | |
| SCHEMBL2846414 | 0.82 | GABRA1 (0.48) | LTA4HCNR2NR5A1KMT2ACNR1 | |
| SCHEMBL1050330 | 0.80 | LTA4H (0.60) | LTA4HNR5A1KMT2ACA12CA1 | |
| SCHEMBL338731 | 0.80 | LTA4H (0.60) | LTA4HNR5A1KMT2ACA12CA1 | |
| SCHEMBL4477939 | 0.79 | LTA4H (0.47) | LTA4HCNR2NR5A1KMT2ACNR1 | |
| SCHEMBL17534283 | 0.79 | LTA4H (0.55) | LTA4HCNR2NR5A1KMT2ACA12 | |
| SCHEMBL6244383 | 0.78 | LTA4H (0.58) | LTA4HNR5A1KMT2ACA12CA1 | |
| SCHEMBL639120 | 0.78 | POLB (0.57) | KMT2A | |
| SCHEMBL4687675 | 0.78 | TUBB4A (0.47) | CNR2CA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021154877-A1 | MITOCHONDRIA-TARGETED ISOKETAL/ISOLEVUGLANDIN SCAVENGERS AND USES THEREOF | VANDERBILT UNIVERSITY (US) | 2021-08-05 | — | — | WO | disclosed |