Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23720531 | 0.91 | MEN1 (0.50) | RAB9AKMT2AMEN1HPGDTSHR | |
| SCHEMBL23720523 | 0.90 | MEN1 (0.49) | RAB9AKMT2AMEN1HPGDTSHR | |
| SCHEMBL23720519 | 0.90 | MEN1 (0.49) | RAB9AKMT2AMEN1HPGDTSHR | |
| SCHEMBL7519591 | 0.78 | GAA (0.60) | RAB9AKMT2AHPGDTSHRNPC1 | |
| SCHEMBL8862746 | 0.78 | GAA (0.60) | RAB9AKMT2AHPGDTSHRNPC1 | |
| SCHEMBL8862856 | 0.78 | GAA (0.60) | RAB9AKMT2AHPGDTSHRNPC1 | |
| SCHEMBL8862940 | 0.78 | GAA (0.60) | RAB9AKMT2AHPGDTSHRNPC1 | |
| SCHEMBL2743018 | 0.77 | HPGD (0.61) | RAB9AKMT2AHPGDTSHRNPC1 | |
| SCHEMBL29132345 | 0.75 | RAB9A (0.52) | RAB9AHPGDTSHRNPC1NPSR1 | |
| SCHEMBL3591703 | 0.75 | HPGD (0.74) | RAB9AKMT2AMEN1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155006-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASES AND USES THEREOF | LES LABORATOIRES SERVIER SAS (FR) | 2021-08-05 | — | — | WO | disclosed |