Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | TYR | P14679 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | GLS | O94925 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL816698 | 0.87 | MAPK1 (0.57) | RAB9AHPGDNPSR1MAPK1NPC1 | |
| SCHEMBL613784 | 0.84 | RAB9A (0.63) | RAB9AHPGDNPSR1MAPK1NPC1 | |
| SCHEMBL9760236 | 0.84 | SMN1; SMN2 (0.51) | RAB9AMAPK1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL23043116 | 0.82 | MEN1 (0.45) | RAB9AHPGDNPSR1MAPK1NPC1 | |
| SCHEMBL26813218 | 0.82 | SMN1; SMN2 (0.53) | RAB9AMAPK1SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7519591 | 0.82 | GAA (0.60) | RAB9AHPGDNPSR1NPC1SMN1; SMN2 | |
| SCHEMBL8862856 | 0.82 | GAA (0.60) | RAB9AHPGDNPSR1NPC1SMN1; SMN2 | |
| SCHEMBL8862940 | 0.82 | GAA (0.60) | RAB9AHPGDNPSR1NPC1SMN1; SMN2 | |
| SCHEMBL8862746 | 0.82 | GAA (0.60) | RAB9AHPGDNPSR1NPC1SMN1; SMN2 | |
| SCHEMBL23043410 | 0.81 | MAOB (0.52) | RAB9AHPGDNPSR1NPC1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240247007-A1 | CHEMICALLY LINKABLE NUCLEAR TARGETING TAGS | SIGMA-ALDRICH CO. LLC | 2024-07-25 | — | — | US | disclosed |
| CN-117279924-A | Chemically-ligatable nuclear targeting tags | 西格马-奥尔德里奇有限责任公司 | 2023-12-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240247007-A1 | CHEMICALLY LINKABLE NUCLEAR TARGETING TAGS | KPNA6, KPNB1, NUP93 | RAB9A 2777/4885TYR 4275/4885HPGD 2625/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.