Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23720523 | 0.99 | MEN1 (0.49) | MEN1KMT2ARAB9AMAPTSMN1; SMN2 | |
| SCHEMBL23720519 | 0.99 | MEN1 (0.49) | MEN1KMT2ARAB9AMAPTSMN1; SMN2 | |
| SCHEMBL23720527 | 0.91 | RAB9A (0.52) | MEN1KMT2ARAB9AMAPTSMN1; SMN2 | |
| SCHEMBL10337042 | 0.79 | MAPT (0.64) | MEN1KMT2ARAB9AMAPTSMN1; SMN2 | |
| SCHEMBL2147069 | 0.78 | RAB9A (0.69) | KMT2ARAB9AMAPTSMN1; SMN2HPGD | |
| SCHEMBL10557663 | 0.76 | MAPT (0.69) | MEN1KMT2ARAB9AMAPTSMN1; SMN2 | |
| SCHEMBL8960362 | 0.75 | RAB9A (0.56) | MEN1KMT2ARAB9AMAPTSMN1; SMN2 | |
| SCHEMBL13909710 | 0.75 | RAB9A (0.55) | RAB9AMAPTSMN1; SMN2TDP1L3MBTL1 | |
| SCHEMBL23720317 | 0.75 | LSS (0.39) | RAB9AMAPTSMN1; SMN2HPGDLMNA | |
| SCHEMBL23100892 | 0.75 | RAB9A (0.55) | RAB9AMAPTSMN1; SMN2TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155006-A1 | INHIBITORS OF CYCLIN-DEPENDENT KINASES AND USES THEREOF | LES LABORATOIRES SERVIER SAS (FR) | 2021-08-05 | — | — | WO | disclosed |