Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 17/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23720763 | 0.67 | MAP3K5 (0.37) | CBLB | |
| SCHEMBL23721141 | 0.59 | MAP3K5 (0.45) | CBLB | |
| SCHEMBL22738993 | 0.57 | MAP3K5 (0.42) | CBLB | |
| SCHEMBL23721207 | 0.56 | MAP3K5 (0.45) | — | |
| SCHEMBL23721183 | 0.56 | CBLB (0.41) | CBLB | |
| SCHEMBL8842567 | 0.52 | CBLB (0.52) | CBLB | |
| SCHEMBL25492039 | 0.49 | CA12 (0.38) | — | |
| SCHEMBL16363837 | 0.49 | AKT1 (0.41) | — | |
| SCHEMBL24977131 | 0.47 | CES2 (0.33) | — | |
| SCHEMBL30236724 | 0.47 | KDM4E (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3363797-B1 | ORAL DOSAGE FORM OF APOPTOSIS SIGNAL-REGULATING KINASE INHIBITORS | GILEAD SCIENCES INC (US) | 2020-12-02 | — | — | EP | disclosed |