Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23721107 | 0.87 | MAPT (0.53) | L3MBTL1TSHRHPGDHSD17B10RAB9A | |
| SCHEMBL4085081 | 0.85 | HTR3E (0.66) | TSHRHPGDHSD17B10MAPTKMT2A | |
| SCHEMBL4085042 | 0.84 | KMT2A (0.61) | L3MBTL1TSHRGLAGAAHPGD | |
| SCHEMBL4095705 | 0.83 | KMT2A (0.64) | L3MBTL1TSHRGLAGAAHPGD | |
| SCHEMBL4084809 | 0.81 | KDM4E (0.64) | TSHRGLAGAAHPGDHSD17B10 | |
| SCHEMBL23721036 | 0.77 | MAPT (0.54) | L3MBTL1TSHRGAAHPGDHSD17B10 | |
| SCHEMBL23720790 | 0.76 | ABCG2 (0.67) | MAPTSMN1; SMN2 | |
| SCHEMBL23657801 | 0.76 | TLR7 (0.72) | L3MBTL1TSHRGLAGAAHPGD | |
| SCHEMBL1083762 | 0.70 | RAB9A (0.77) | L3MBTL1TSHRGLAGAAHPGD | |
| SCHEMBL23107995 | 0.69 | OGA (0.43) | L3MBTL1TSHRGLAGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2938608-B1 | SMALL MOLECULE AGONISTS OF NEUROTENSIN RECEPTOR 1 | SANFORD BURNHAM MED RES INST (US) | 2021-08-04 | — | — | EP | disclosed |