Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.54 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.51 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23720790 | 0.87 | ABCG2 (0.67) | MAPTABCG2 | |
| SCHEMBL4085081 | 0.80 | HTR3E (0.66) | MAPTALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL4085042 | 0.80 | KMT2A (0.61) | MAPTALDH1A1KDM4EHPGDGAA | |
| SCHEMBL4095705 | 0.79 | KMT2A (0.64) | MAPTALDH1A1KDM4EHPGDGAA | |
| SCHEMBL23720822 | 0.77 | L3MBTL1 (0.50) | MAPTNTSR1ALDH1A1KDM4EHPGD | |
| SCHEMBL4084809 | 0.77 | KDM4E (0.64) | MAPTALDH1A1KDM4EHPGDGAA | |
| SCHEMBL23721107 | 0.75 | MAPT (0.53) | MAPTNTSR1ALDH1A1KDM4EHPGD | |
| SCHEMBL11096302 | 0.73 | KCNH2 (0.73) | MAPTALDH1A1HPGDGAAADRB1 | |
| SCHEMBL11103700 | 0.72 | ADRB1 (0.74) | MAPTALDH1A1ADRB1KCNH2RAB9A | |
| SCHEMBL10373770 | 0.72 | ADRB1 (0.74) | MAPTALDH1A1ADRB1KCNH2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2938608-B1 | SMALL MOLECULE AGONISTS OF NEUROTENSIN RECEPTOR 1 | SANFORD BURNHAM MED RES INST (US) | 2021-08-04 | — | — | EP | disclosed |