Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL947151 | 0.76 | MAP3K5 (0.58) | MAP3K5 | |
| SCHEMBL946461 | 0.76 | MAP3K5 (0.48) | MAP3K5 | |
| SCHEMBL944284 | 0.74 | GSK3B (0.32) | — | |
| SCHEMBL22738988 | 0.65 | MAP3K5 (0.33) | MAP3K5 | |
| SCHEMBL22739206 | 0.65 | MAP3K5 (0.48) | MAP3K5 | |
| SCHEMBL17180511 | 0.64 | MAP3K5 (0.45) | MAP3K5 | |
| SCHEMBL945044 | 0.64 | MAP3K5 (0.59) | MAP3K5 | |
| SCHEMBL944993 | 0.63 | MAP3K5 (0.50) | MAP3K5 | |
| SCHEMBL22739074 | 0.63 | MAP3K5 (0.43) | MAP3K5 | |
| SCHEMBL23721179 | 0.63 | CBLB (0.35) | MAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858824-A1 | APOPTOSIS SIGNAL-REGULATING KINASE INHIBITORS | Gilead Sciences, Inc. (US) | 2021-08-04 | — | — | EP | disclosed |