Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL946000 | 0.65 | PDE3B (0.43) | MAP3K5 | |
| SCHEMBL23720983 | 0.65 | MAP3K5 (0.32) | MAP3K5 | |
| SCHEMBL22739206 | 0.63 | MAP3K5 (0.48) | MAP3K5 | |
| SCHEMBL22739074 | 0.60 | MAP3K5 (0.43) | MAP3K5 | |
| SCHEMBL22739085 | 0.59 | MAP3K5 (0.30) | MAP3K5 | |
| SCHEMBL23720730 | 0.58 | MAP3K5 (0.36) | MAP3K5 | |
| SCHEMBL17180511 | 0.57 | MAP3K5 (0.45) | MAP3K5 | |
| SCHEMBL28848830 | 0.57 | PDE3B (0.43) | MAP3K5 | |
| SCHEMBL28848713 | 0.57 | PDE3B (0.43) | MAP3K5 | |
| SCHEMBL945044 | 0.56 | MAP3K5 (0.59) | MAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3363797-B1 | ORAL DOSAGE FORM OF APOPTOSIS SIGNAL-REGULATING KINASE INHIBITORS | GILEAD SCIENCES INC (US) | 2020-12-02 | — | — | EP | disclosed |