Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 19/20 | 0.61 |
| ▸ | HTR2A | P28223 | 15/20 | 0.57 |
| ▸ | HTR1A | P08908 | 12/20 | 0.57 |
| ▸ | DRD4 | P21917 | 2/20 | 0.48 |
| ▸ | DRD1 | P21728 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23722211 | 0.91 | DRD2 (0.56) | DRD2HTR2AHTR1ADRD4DRD1 | |
| SCHEMBL23720956 | 0.90 | DRD2 (0.59) | DRD2HTR2AHTR1ADRD4DRD1 | |
| SCHEMBL23721414 | 0.87 | DRD2 (0.59) | DRD2HTR2AHTR1ADRD4DRD1 | |
| SCHEMBL24654555 | 0.86 | DRD2 (0.63) | DRD2HTR2AHTR1ADRD4DRD1 | |
| SCHEMBL23721758 | 0.86 | DRD2 (0.67) | DRD2HTR2AHTR1ADRD3 | |
| SCHEMBL23721397 | 0.85 | DRD2 (0.61) | DRD2HTR2AHTR1ADRD4DRD1 | |
| SCHEMBL23721794 | 0.85 | DRD2 (0.61) | DRD2HTR2AHTR1ADRD4DRD1 | |
| SCHEMBL24654638 | 0.84 | DRD2 (0.56) | DRD2HTR2AHTR1ADRD4DRD1 | |
| SCHEMBL24654611 | 0.83 | DRD2 (0.60) | DRD2HTR2AHTR1ADRD4DRD1 | |
| SCHEMBL24654560 | 0.83 | DRD2 (0.59) | DRD2HTR2AHTR1ADRD4DRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2445343-B1 | PRODRUGS OF NH-ACIDIC COMPOUNDS | ALKERMES PHARMA IRELAND LTD (IE) | 2021-08-04 | — | — | EP | disclosed |