Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 11/20 | 0.35 |
| ▸ | AKT1 | P31749 | 3/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL947106 | 0.72 | MAP3K5 (0.65) | MAP3K5AKT1 | |
| SCHEMBL23721179 | 0.67 | CBLB (0.35) | MAP3K5 | |
| SCHEMBL16848415 | 0.65 | MAP3K5 (0.65) | MAP3K5 | |
| SCHEMBL22739206 | 0.64 | MAP3K5 (0.48) | MAP3K5 | |
| SCHEMBL23720730 | 0.64 | MAP3K5 (0.36) | MAP3K5 | |
| SCHEMBL942523 | 0.63 | MAP3K5 (0.64) | MAP3K5 | |
| SCHEMBL945130 | 0.62 | MAP3K5 (0.58) | MAP3K5 | |
| SCHEMBL23721196 | 0.62 | MAP3K5 (0.34) | MAP3K5 | |
| SCHEMBL944011 | 0.61 | MAP3K5 (0.55) | MAP3K5AKT1 | |
| SCHEMBL23720983 | 0.60 | MAP3K5 (0.32) | MAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858824-A1 | APOPTOSIS SIGNAL-REGULATING KINASE INHIBITORS | Gilead Sciences, Inc. (US) | 2021-08-04 | — | — | EP | disclosed |