Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.36 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.30 |
| ▸ | CBLB | Q13191 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23721197 | 0.86 | CBLB (0.31) | MAP3K5CBLB | |
| SCHEMBL22739074 | 0.79 | MAP3K5 (0.43) | MAP3K5 | |
| SCHEMBL22739085 | 0.76 | MAP3K5 (0.30) | MAP3K5 | |
| SCHEMBL23721196 | 0.73 | MAP3K5 (0.34) | MAP3K5CBLB | |
| SCHEMBL22739290 | 0.71 | EGFR (0.33) | — | |
| SCHEMBL22739020 | 0.71 | — | — | |
| SCHEMBL945922 | 0.70 | MAP3K5 (0.66) | MAP3K5CBLB | |
| SCHEMBL23721179 | 0.68 | CBLB (0.35) | MAP3K5CBLB | |
| SCHEMBL23721303 | 0.67 | PIK3C3 (0.42) | MAP3K5PIK3C3 | |
| SCHEMBL14681924 | 0.66 | MAP3K5 (0.60) | MAP3K5CBLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3858824-A1 | APOPTOSIS SIGNAL-REGULATING KINASE INHIBITORS | Gilead Sciences, Inc. (US) | 2021-08-04 | — | — | EP | disclosed |