Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QDPR | P09417 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 4/20 | 0.31 |
| ▸ | DRD4 | P21917 | 4/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15322858 | 0.79 | CDK4 (0.40) | QDPR | |
| SCHEMBL21400719 | 0.79 | CDK4 (0.40) | QDPR | |
| SCHEMBL14388734 | 0.69 | QDPR (0.36) | QDPRDRD2DRD4KMT2A | |
| SCHEMBL14404662 | 0.68 | QDPR (0.33) | QDPR | |
| SCHEMBL24365923 | 0.68 | RAD52 (0.33) | QDPR | |
| SCHEMBL14388737 | 0.67 | ALDH1A1 (0.34) | QDPRDRD2DRD4KMT2A | |
| SCHEMBL5475515 | 0.67 | QDPR (0.37) | QDPRGAA | |
| SCHEMBL5475514 | 0.67 | QDPR (0.33) | QDPR | |
| SCHEMBL31566807 | 0.66 | THRB (0.45) | — | |
| SCHEMBL1629925 | 0.66 | PHGDH (0.42) | MEN1USP2GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2938608-B1 | SMALL MOLECULE AGONISTS OF NEUROTENSIN RECEPTOR 1 | SANFORD BURNHAM MED RES INST (US) | 2021-08-04 | — | — | EP | disclosed |