Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | GBA1 | P04062 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL574791 | 0.76 | MAPK1 (0.64) | ALDH1A1LMNASMN1; SMN2PKMKEAP1 | |
| SCHEMBL19280574 | 0.76 | ALDH1A1 (0.56) | ALDH1A1LMNASMN1; SMN2PKMKEAP1 | |
| SCHEMBL3528919 | 0.76 | CYP2C19 (0.57) | ALDH1A1LMNASMN1; SMN2PKMKEAP1 | |
| SCHEMBL2595618 | 0.74 | ALDH1A1 (0.55) | ALDH1A1LMNASMN1; SMN2PKMKEAP1 | |
| SCHEMBL3686095 | 0.73 | ALDH1A1 (0.61) | ALDH1A1LMNASMN1; SMN2PKMKEAP1 | |
| SCHEMBL2372214 | 0.73 | CA1 (0.44) | ALDH1A1LMNASMN1; SMN2PKMKEAP1 | |
| SCHEMBL6008583 | 0.73 | ALDH1A1 (0.53) | ALDH1A1LMNASMN1; SMN2PKMKEAP1 | |
| SCHEMBL6008587 | 0.73 | ALDH1A1 (0.53) | ALDH1A1LMNASMN1; SMN2PKMKEAP1 | |
| SCHEMBL3651548 | 0.72 | ALDH1A1 (0.61) | ALDH1A1LMNASMN1; SMN2PKMKEAP1 | |
| SCHEMBL5518065 | 0.72 | KEAP1 (0.65) | ALDH1A1LMNASMN1; SMN2KEAP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2547204-A2 | ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS | Bayer Intellectual Property GmbH (DE) | 2013-01-23 | — | — | EP | disclosed |
| WO-2011113861-A2 | ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2011-09-22 | — | — | WO | disclosed |