SCHEMBL2372274

SCHEMBL2372274

Cc1ccc(S(=O)(=O)N[C]2CC2)c2ccccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.43
MAPT P10636 1/20 0.43
FABP4 P15090 2/20 0.42
SMN1; SMN2 Q16637 3/20 0.41
HPGD P15428 2/20 0.41
LMNA P02545 1/20 0.41
ALDH1A1 P00352 4/20 0.41
MAPK1 P28482 1/20 0.41
MEN1 O00255 5/20 0.40
KMT2A Q03164 5/20 0.40
GAA P10253 2/20 0.40
G6PD P11413 1/20 0.40
MAP1LC3B Q9GZQ8 1/20 0.40
KDM4E B2RXH2 1/20 0.39
RXFP1 Q9HBX9 1/20 0.39
PKM P14618 1/20 0.38
HCRTR1 O43613 1/20 0.38
BRD4 O60885 1/20 0.38
HTT P42858 1/20 0.38
CCR8 P51685 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2371075 0.80 RXFP1 (0.57) FABP4HPGDALDH1A1MAPK1MEN1
SCHEMBL2372369 0.80 GAA (0.56) FABP4ALDH1A1GAAKDM4EHTT
SCHEMBL2371911 0.80 FABP4 (0.60) FABP4SMN1; SMN2LMNAALDH1A1MAPK1
SCHEMBL2371608 0.77 CYP1A2 (0.48) CYP1A2MAPTFABP4SMN1; SMN2HPGD
SCHEMBL2385512 0.76 FABP4 (0.44) CYP1A2MAPTFABP4SMN1; SMN2HPGD
SCHEMBL16261195 0.76 NSD2 (0.58) CYP1A2MAPTFABP4SMN1; SMN2HPGD
SCHEMBL2372573 0.76 HCRTR1 (0.58) CYP1A2ALDH1A1MEN1KMT2AKDM4E
SCHEMBL16852786 0.74 PARG (0.44) CYP1A2MAPTGAAHTTCCR8
SCHEMBL2442796 0.73 TSHR (0.43) CYP1A2LMNAKDM4EHCRTR1
SCHEMBL2372245 0.73 FABP4 (0.47) MAPTFABP4MEN1KMT2ARXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2547204-A2 ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS Bayer Intellectual Property GmbH (DE) 2013-01-23 EP claimed
US-20110230350-A1 ARYL-AND HETARYLSULFONAMIDES AS ACTIVE INGREDIENTS AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2011-09-22 US claimed
WO-2011113861-A2 ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2011-09-22 WO claimed
EP-2547204-A2 ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS Bayer Intellectual Property GmbH (DE) 2013-01-23 EP disclosed
US-20110230350-A1 ARYL-AND HETARYLSULFONAMIDES AS ACTIVE INGREDIENTS AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2011-09-22 US disclosed
WO-2011113861-A2 ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2011-09-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110230350-A1 ARYL-AND HETARYLSULFONAMIDES AS ACTIVE INGREDIENTS AGAINST ABIOTIC PLANT STRESS STS, ARSA, TST CYP1A2 129/4885MAPT 4663/4885FABP4 2682/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.