Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.57 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.57 |
| ▸ | HTR3B | O95264 | 3/20 | 0.57 |
| ▸ | HTR3A | P46098 | 3/20 | 0.57 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.57 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.57 |
| ▸ | KLK7 | P49862 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1460522 | 0.81 | CHRNA7 (0.69) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL7122170 | 0.81 | CHRNA7 (0.61) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL1459742 | 0.81 | HTR3A (0.67) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL5266545 | 0.79 | HTR3A (0.58) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL23722866 | 0.79 | KDM4E (0.67) | USP30CYP3A4KDM4ESMN1; SMN2KLK7 | |
| SCHEMBL14970878 | 0.79 | KDM4E (0.75) | USP30CYP3A4KDM4ESMN1; SMN2KLK7 | |
| SCHEMBL2951170 | 0.78 | HTR3A (0.60) | CHRNA7HTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL18115676 | 0.78 | USP30 (1.00) | USP30KDM4ESMN1; SMN2KLK7KMT2A | |
| SCHEMBL29779110 | 0.78 | USP30 (1.00) | USP30KDM4ESMN1; SMN2KLK7KMT2A | |
| SCHEMBL6655690 | 0.77 | CHRNA7 (0.65) | CHRNA7HTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210244721-A1 | SMALL MOLECULE ENTEROVIRUS INHIBITORS AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2021-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210244721-A1 | SMALL MOLECULE ENTEROVIRUS INHIBITORS AND USES THEREOF | AR, KLK3, BRDT | USP30 3750/4885CYP3A4 856/4885KDM4E 2146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.