Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 10/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.54 |
| ▸ | HTR3E | A5X5Y0 | 4/20 | 0.54 |
| ▸ | HTR3B | O95264 | 4/20 | 0.54 |
| ▸ | HTR3D | Q70Z44 | 4/20 | 0.54 |
| ▸ | HTR3C | Q8WXA8 | 4/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1032402 | 0.86 | CHRNA7 (0.52) | HTR3AKCNH2CHRNA7 | |
| SCHEMBL5268531 | 0.84 | HTR3A (0.61) | HTR3AKCNH2 | |
| SCHEMBL5267272 | 0.81 | HTR3A (0.63) | HTR3AKCNH2CHRNA7HTR3EHTR3B | |
| SCHEMBL5270359 | 0.81 | HTR3A (0.63) | HTR3AKCNH2CHRNA7HTR3EHTR3B | |
| SCHEMBL5269864 | 0.81 | HTR3A (0.62) | HTR3AKCNH2 | |
| SCHEMBL7122170 | 0.81 | CHRNA7 (0.61) | HTR3ACHRNA7HTR3EHTR3BHTR3D | |
| SCHEMBL2962024 | 0.79 | HTR3A (0.73) | HTR3AKCNH2CHRNA7HTR3EHTR3B | |
| SCHEMBL5264415 | 0.79 | HTR3A (0.61) | HTR3AKCNH2 | |
| SCHEMBL23722904 | 0.79 | USP30 (0.63) | HTR3ACHRNA7HTR3EHTR3BHTR3D | |
| SCHEMBL1460522 | 0.79 | CHRNA7 (0.69) | HTR3ACHRNA7HTR3EHTR3BHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448530-B1 | HETEROARYL CARBOXYLIC ACID AMIDES | BAYER HEALTHCARE AG (DE) | 2007-10-03 | — | — | EP | disclosed |