Sugi Predict

Sugi Predict / Compounds / SCHEMBL23722969

SCHEMBL23722969

SCHEMBL23722969

CN(C(=O)OCC1c2ccccc2-c2ccccc21)C(CSC(c1ccccc1)(c1ccccc1)c1ccccc1)C(=O)O

nearest known ligand 0.40

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ KIF11 P52732 15/20 0.40
▸ KMT2A Q03164 1/20 0.39
▸ MDM4 O15151 1/20 0.39
▸ TP53 P04637 1/20 0.39
▸ FABP5 Q01469 2/20 0.38
▸ FABP7 O15540 1/20 0.38
▸ DNMT1 P26358 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4409339 1.00 KIF11 (0.40) KIF11KMT2AMDM4TP53FABP5
SCHEMBL29611191 1.00 KIF11 (0.40) KIF11KMT2AMDM4TP53FABP5
SCHEMBL31714132 1.00 KIF11 (0.40) KIF11KMT2AMDM4TP53FABP5
SCHEMBL29511437 1.00 KIF11 (0.40) KIF11KMT2AMDM4TP53FABP5
SCHEMBL31370691 0.93 KIF11 (0.52) KIF11MDM4TP53FABP5DNMT1
SCHEMBL30471578 0.93 KIF11 (0.52) KIF11MDM4TP53FABP5DNMT1
SCHEMBL2814403 0.90 FABP5 (0.39) KIF11KMT2AMDM4TP53FABP5
SCHEMBL2814407 0.90 FABP5 (0.39) KIF11KMT2AMDM4TP53FABP5
SCHEMBL4406592 0.88 KIF11 (0.39) KIF11KMT2AMDM4TP53FABP5
SCHEMBL4406195 0.87 MDM4 (0.39) KIF11KMT2AMDM4TP53FABP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3966226-B1 MASP INHIBITORY COMPOUNDS AND USES THEREOF BAYER AG (DE) 2025-12-24 — — EP disclosed
US-12503491-B2 MASP inhibitory compounds and uses thereof BAYER AKTIENGESELLSCHAFT (DE) 2025-12-23 — — US disclosed
WO-2025070720-A1 PEPTIDE ペプチドリーム株式会社 2025-04-03 — — WO disclosed
WO-2025070731-A1 PEPTIDEPEPTIDE ペプチドリーム株式会社 2025-04-03 — — WO disclosed
US-20240124522-A1 MASP INHIBITORY COMPOUNDS AND USES THEREOF BAYER AKTIENGESELLSCHAFT (DE) 2024-04-18 — — US disclosed
US-20240010684-A1 MASP INHIBITORY COMPOUNDS AND USES THEREOF BAYER AG (DE) 2024-01-11 — — US disclosed
US-11667675-B2 MASP inhibitory compounds and uses thereof BAYER AKTIENGESELLSCHAFT (DE) 2023-06-06 — — US disclosed
EP-4011904-A1 MASP INHIBITORY COMPOUNDS AND USES THEREOF Bayer Aktiengesellschaft (DE) 2022-06-15 — — EP disclosed
US-20210246166-A1 MASP INHIBITORY COMPOUNDS AND USES THEREOF BAYER AKTIENGESELLSCHAFT (DE) 2021-08-12 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12503491-B2 MASP inhibitory compounds and uses thereof MASP2, SERPINB1, SPINT2 KIF11 4273/4885KMT2A 4690/4885MDM4 2629/4885
US-11667675-B2 MASP inhibitory compounds and uses thereof MASP2, SERPINB1, SPINT2 KIF11 4273/4885KMT2A 4690/4885MDM4 2629/4885
US-20240124522-A1 MASP INHIBITORY COMPOUNDS AND USES THEREOF MASP2, SERPINB1, SPINT2 KIF11 4273/4885KMT2A 4690/4885MDM4 2629/4885
US-20210246166-A1 MASP INHIBITORY COMPOUNDS AND USES THEREOF MASP2, SERPINB1, SPINT2 KIF11 4273/4885KMT2A 4690/4885MDM4 2629/4885
US-20240010684-A1 MASP INHIBITORY COMPOUNDS AND USES THEREOF MASP2, SPINT2, SERPINB1 KIF11 4338/4885KMT2A 4666/4885MDM4 3411/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.