SCHEMBL23723352

SCHEMBL23723352

Cc1c(I)c2cc(Br)ccc2n1C(=O)OC(C)(C)C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDK1 P06493 2/20 0.47
CCNB2 O95067 1/20 0.47
CCNB1 P14635 1/20 0.47
GSK3B P49841 1/20 0.47
CCNB3 Q8WWL7 1/20 0.47
GABRG2 P18507 2/20 0.45
GABRB3 P28472 2/20 0.45
GABRA5 P31644 2/20 0.45
GABRA1 P14867 1/20 0.38
GABRA2 P47869 1/20 0.38
GABRA6 Q16445 1/20 0.38
BACE1 P56817 1/20 0.36
NR1H2 P55055 2/20 0.36
KRAS P01116 2/20 0.35
BAZ2B Q9UIF8 1/20 0.35
USP30 Q70CQ3 2/20 0.35
CHRM2 P08172 1/20 0.34
CHRM4 P08173 1/20 0.34
CHRM1 P11229 1/20 0.34
CHRM3 P20309 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18941218 0.86 CDK1 (0.49) CDK1CCNB2CCNB1GSK3BCCNB3
SCHEMBL409607 0.84 CDK1 (0.54) CDK1CCNB2CCNB1GSK3BCCNB3
SCHEMBL2186140 0.81 CCNB2 (0.49) CDK1CCNB2CCNB1GSK3BCCNB3
SCHEMBL19418900 0.81 CHRM2 (0.48) GABRG2GABRB3GABRA5NR1H2CHRM2
SCHEMBL3381222 0.80 CDK1 (0.45) CDK1CCNB2CCNB1GSK3BCCNB3
SCHEMBL3197264 0.79 CDK1 (0.47) CDK1CCNB2CCNB1GSK3BCCNB3
SCHEMBL22463497 0.79 CDK1 (0.45) CDK1CCNB2CCNB1GSK3BCCNB3
SCHEMBL802084 0.78 CDK1 (0.54) CDK1CCNB2CCNB1GSK3BCCNB3
SCHEMBL29357718 0.78 CDK1 (0.54) CDK1CCNB2CCNB1GSK3BCCNB3
SCHEMBL13478527 0.77 CCNB2 (0.42) CDK1CCNB2CCNB1GSK3BCCNB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12578335-B2 Bioprobes for lysyl oxidases and uses thereof SYNTARA LIMITED (AU) 2026-03-17 US disclosed
US-20230349907-A1 BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF PHARMAXIS LTD. (AU) 2023-11-02 US disclosed
WO-2021155439-A1 BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF PHARMAXIS LTD. (AU) 2021-08-12 WO disclosed
WO-2021155439-A1 BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF PHARMAXIS LTD. (AU) 2021-08-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230349907-A1 BIOPROBES FOR LYSYL OXIDASES AND USES THEREOF MAOB, LOX, LPO CDK1 4172/4885CCNB2 3233/4885CCNB1 3122/4885
US-12578335-B2 Bioprobes for lysyl oxidases and uses thereof LOXL1, LOX, LOXL2 CDK1 3667/4885CCNB2 3303/4885CCNB1 2773/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.