Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 7/20 | 0.64 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.64 |
| ▸ | AHCY | P23526 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.57 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.57 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.57 |
| ▸ | LDHA | P00338 | 1/20 | 0.57 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.57 |
| ▸ | FBP1 | P09467 | 1/20 | 0.57 |
| ▸ | SRC | P12931 | 1/20 | 0.57 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.57 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.57 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.57 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.57 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.57 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2373115 | 0.98 | ADORA2A (0.64) | ADORA1ADORA2AAHCYSMN1; SMN2DNPH1 | |
| SCHEMBL8607675 | 0.86 | ADORA1 (0.64) | ADORA1ADORA2AAHCYSMN1; SMN2DNPH1 | |
| SCHEMBL8606022 | 0.86 | ADORA1 (0.64) | ADORA1ADORA2AAHCYSMN1; SMN2DNPH1 | |
| SCHEMBL622588 | 0.85 | ADORA1 (0.69) | ADORA1ADORA2AAHCYSMN1; SMN2DNPH1 | |
| SCHEMBL123718 | 0.85 | ADORA1 (0.61) | ADORA1ADORA2AAHCYSMN1; SMN2DNPH1 | |
| SCHEMBL7459994 | 0.85 | ADORA1 (0.61) | ADORA1ADORA2AAHCYSMN1; SMN2DNPH1 | |
| SCHEMBL8606410 | 0.85 | ADORA1 (0.64) | ADORA1ADORA2AAHCYSMN1; SMN2DNPH1 | |
| SCHEMBL5272719 | 0.85 | ADORA1 (0.68) | ADORA1ADORA2AAHCYSMN1; SMN2DNPH1 | |
| SCHEMBL8606939 | 0.85 | ADORA1 (0.64) | ADORA1ADORA2AAHCYSMN1; SMN2DNPH1 | |
| SCHEMBL120551 | 0.81 | ADORA3 (0.69) | ADORA1ADORA2AAHCYSMN1; SMN2DNPH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8501708-B2 | Adenosine compounds and their use thereof | INOTEK PHARMACEUTICALS CORPORATION (US) | 2013-08-06 | — | — | US | disclosed |
| EP-2552932-A1 | ADENOSINE COMPOUNDS AND THEIR USE THEREOF | Inotek Pharmaceuticals Corporation (US) | 2013-02-06 | — | — | EP | disclosed |
| US-20110245194-A1 | ADENOSINE COMPOUNDS AND THEIR USE THEREOF | INOTEK PHARMACEUTICALS CORPORATION (US) | 2011-10-06 | — | — | US | disclosed |
| WO-2011119919-A1 | ADENOSINE COMPOUNDS AND THEIR USE THEREOF | INOTEK PHARMACEUTICALS CORPORATION (US) | 2011-09-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110245194-A1 | ADENOSINE COMPOUNDS AND THEIR USE THEREOF | ADORA1, ADORA2A, ADORA3 | ADORA1 1/4885ADORA2A 2/4885AHCY 89/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.