Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 5/20 | 0.68 |
| ▸ | AHCY | P23526 | 3/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.64 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.64 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.64 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.64 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.64 |
| ▸ | DPP4 | P27487 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.64 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.64 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.64 |
| ▸ | GAPDH | P04406 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | STAT6 | P42226 | 1/20 | 0.64 |
| ▸ | PI4KA | P42356 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.64 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL622588 | 0.91 | ADORA1 (0.69) | ADORA1AHCYSMN1; SMN2ADORA3ADORA2A | |
| SCHEMBL5276197 | 0.89 | TRDMT1 (0.60) | ADORA1SMN1; SMN2ADORA3ADORA2AADORA2B | |
| SCHEMBL5271641 | 0.88 | ADORA2A (0.58) | ADORA1SMN1; SMN2ADORA3ADORA2AADORA2B | |
| SCHEMBL109340 | 0.86 | P2RY1 (0.72) | ADORA1AHCYSMN1; SMN2P2RY1P2RY2 | |
| SCHEMBL6905464 | 0.86 | ADORA1 (0.72) | ADORA1AHCYSMN1; SMN2ADORA3ADORA2A | |
| SCHEMBL1434032 | 0.86 | ADORA1 (0.72) | ADORA1AHCYSMN1; SMN2ADORA3ADORA2A | |
| SCHEMBL22458248 | 0.86 | ADORA1 (0.65) | ADORA1AHCYSMN1; SMN2ADORA3ADORA2A | |
| SCHEMBL1434130 | 0.85 | ADORA1 (0.67) | ADORA1AHCYSMN1; SMN2ADORA3ADORA2A | |
| SCHEMBL3446755 | 0.85 | ADORA1 (0.71) | ADORA1AHCYSMN1; SMN2ADORA3ADORA2A | |
| SCHEMBL2372390 | 0.85 | ADORA1 (0.64) | ADORA1AHCYSMN1; SMN2ADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013165898-A2 | COMPOSITIONS AND METHODS FOR INHIBITING RESOLVASES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2013-11-07 | — | — | WO | disclosed |
| EP-1868628-A2 | COMPOUNDS, COMPOSITIONS AND METHODS FOR THE TREATMENT OF POXVIRUS INFECTIONS | Chimerix, Inc. (US) | 2007-12-26 | — | — | EP | disclosed |
| WO-2006110655-A2 | COMPOUNDS, COMPOSITIONS AND METHODS FOR THE TREATMENT OF POXVIRUS INFECTIONS | CHIMERIX, INC. (US) | 2006-10-19 | — | — | WO | disclosed |
| WO-1998016539-A1 | NOVEL THERAPEUTICALLY ACTIVE ADENOSINE DERIVATIVES | NOVO NORDISK A/S (DK) | 1998-04-23 | — | — | WO | disclosed |