SCHEMBL2372569

SCHEMBL2372569

C[CH]NS(=O)(=O)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 2/20 0.54
CA1 P00915 1/20 0.54
MMP1 P03956 1/20 0.54
MMP2 P08253 1/20 0.54
MMP9 P14780 1/20 0.54
MMP8 P22894 1/20 0.54
MMP13 P45452 1/20 0.54
KEAP1 Q14145 2/20 0.52
IL1RN P18510 1/20 0.52
ERAP1 Q9NZ08 1/20 0.52
BCAT1 P54687 2/20 0.48
ALDH1A1 P00352 4/20 0.48
PKM P14618 2/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
FFAR4 Q5NUL3 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
KDM4E B2RXH2 1/20 0.47
LMNA P02545 1/20 0.47
HTR6 P50406 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24223539 0.82 CA2 (0.50) CA2CA1MMP1MMP2MMP9
SCHEMBL8351001 0.82 GAA (0.59) CA2CA1MMP1MMP2MMP9
SCHEMBL92828 0.78 CA1 (0.56) CA2CA1MMP1MMP2MMP9
SCHEMBL3246018 0.76 CA2 (0.54) CA2CA1MMP1MMP2MMP9
SCHEMBL2371757 0.76 CA1 (0.54) CA2CA1MMP1MMP2MMP9
SCHEMBL28290634 0.76 CA1 (0.54) CA2CA1MMP1MMP2MMP9
SCHEMBL27766226 0.76 CA1 (0.54) CA2CA1MMP1MMP2MMP9
SCHEMBL603121 0.76 MMP2 (0.54) CA2CA1MMP1MMP2MMP9
SCHEMBL4911080 0.76 MMP2 (0.54) CA2CA1MMP1MMP2MMP9
SCHEMBL9453817 0.76 CA2 (0.54) CA2CA1MMP1MMP2MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2547204-A2 ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS Bayer Intellectual Property GmbH (DE) 2013-01-23 EP claimed
WO-2011113861-A2 ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2011-09-22 WO claimed
EP-2547204-A2 ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS Bayer Intellectual Property GmbH (DE) 2013-01-23 EP disclosed
WO-2011113861-A2 ARYL AND HETARYL SULFONAMIDES AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS BAYER CROPSCIENCE AG (DE) 2011-09-22 WO disclosed
EP-1696912-A4 PYRAZOLOPYRIDINES AND ANALOGS THEREOF 3M INNOVATIVE PROPERTIES CO (US) 2009-06-03 EP disclosed
EP-1863809-A2 PYRAZOLOPYRIDINES AND ANALOGS THEREOF Coley Pharmaceutical Group, Inc. (US) 2007-12-12 EP disclosed
EP-1850857-A2 ISOLATION OF ATRARIC ACID, SYNTHESIS OF ATRARIC ACID DERIVATIVES, AND USE OF ATRARIC ACID AND THE DERIVATIVES THEREOF FOR THE TREATMENT OF BENIGN PROSTATE HYPERPLASIA, PROSTATE CARCINOMA, AND SPINOBULBAR MUSCULAR ATROPHY LTS LOHMANN Therapie-Systeme AG (DE) 2007-11-07 EP disclosed
WO-2006107753-A2 PYRAZOLOPYRIDINES AND ANALOGS THEREOF COLEY PHARMACEUTICAL GROUP, INC. (US) 2006-10-12 WO disclosed
EP-1696912-A2 PYRAZOLOPYRIDINES AND ANALOGS THEREOF 3M Innovative Properties Company (US) 2006-09-06 EP disclosed
WO-2006081997-A2 ISOLATION OF ATRARIC ACID, SYNTHESIS OF ATRARIC ACID DERIVATIVES, AND USE OF ATRARIC ACID AND THE DERIVATIVES THEREOF FOR THE TREATMENT OF BENIGN PROSTATE HYPERPLASIA, PROSTATE CARCINOMA, AND SPINOBULBAR MUSCULAR ATROPHY LTS LOHMANN THERAPIE-SYSTEMS AG (DE) 2006-08-10 WO disclosed
WO-2005079195-A2 PYRAZOLOPYRIDINES AND ANALOGS THEREOF 3M INNOVATIVE PROPERTIES COMPANY (US) 2005-09-01 WO disclosed
EP-0451824-A2 Chelating compounds and their use NIHON MEDI-PHYSICS CO., LTD. (JP) 1991-10-16 EP disclosed
US-5038415-A Bath stability; level dyeing SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-08-13 US disclosed
EP-0430459-A1 Tetrahydronaphthalene derivatives and preparation thereof TANABE SEIYAKU CO., LTD. (JP) 1991-06-05 EP disclosed
EP-0378167-A1 Disperse dye composition useful for dyeing or printing hydrophobic fiber materials SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-07-18 EP disclosed
EP-0370644-A2 Herbicidal compounds ZENECA LIMITED (GB) 1990-05-30 EP disclosed
EP-0368592-A1 Herbicidal compositions IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1990-05-16 EP disclosed
US-4292238-A Alkylation of benzthiazole-azo-phenylamine dyestuffs BAYER AKTIENGESELLSCHAFT (DE) 1981-09-29 US disclosed
US-4051084-A BENZOTHIAZOLE BAYER AKTIENGESELLSCHAFT (DT) 1977-09-27 US disclosed
US-4039526-A PRINTING, POLYACRYLONITRILE, POLYESTERS, POLYAMIDES BAYER AKTIENGESELLSCHAFT (DT) 1977-08-02 US disclosed