SCHEMBL4911080

SCHEMBL4911080

N=CNS(=O)(=O)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP2 P08253 2/20 0.54
CA1 P00915 1/20 0.54
CA2 P00918 1/20 0.54
MMP1 P03956 1/20 0.54
MMP9 P14780 1/20 0.54
MMP8 P22894 1/20 0.54
MMP13 P45452 1/20 0.54
KEAP1 Q14145 3/20 0.52
IL1RN P18510 1/20 0.52
ERAP1 Q9NZ08 1/20 0.52
ALDH1A1 P00352 3/20 0.48
PKM P14618 2/20 0.48
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
KDM4E B2RXH2 1/20 0.47
LMNA P02545 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
HTR6 P50406 1/20 0.46
PGR P06401 1/20 0.46
BCAT1 P54687 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16452382 0.80 GAA (0.57) MMP2CA1CA2MMP1MMP9
SCHEMBL92828 0.78 CA1 (0.56) MMP2CA1CA2MMP1MMP9
SCHEMBL2372569 0.76 CA2 (0.54) MMP2CA1CA2MMP1MMP9
SCHEMBL3246018 0.76 CA2 (0.54) MMP2CA1CA2MMP1MMP9
SCHEMBL2371757 0.76 CA1 (0.54) MMP2CA1CA2MMP1MMP9
SCHEMBL603121 0.76 MMP2 (0.54) MMP2CA1CA2MMP1MMP9
SCHEMBL3751632 0.75 CA1 (0.58) MMP2CA1CA2MMP1MMP9
SCHEMBL28369244 0.74 MMP2 (0.52) MMP2CA1CA2MMP1MMP9
SCHEMBL5966713 0.74 CA1 (0.52) MMP2CA1CA2MMP1MMP9
SCHEMBL992761 0.74 CA1 (0.64) MMP2CA1CA2MMP1MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114163401-A Preparation method and application of N-benzenesulfonyl formamidine compound 商丘师范学院 2022-03-11 CN claimed
US-20080293674-A1 Azinyl Imidazoazine and Azinyl Carboxamide BAYER CROPSCIENCE AG (DE) 2008-11-27 US claimed
EP-1751152-A2 AZINYL IMIDAZOAZINE AND AZINYL CARBOXAMIDE Bayer CropScience Aktiengesellschaft (DE) 2007-02-14 EP claimed
WO-2005113553-A2 AZINYL IMIDAZOAZINE AND AZINYL CARBOXAMIDE BAYER CROPSCIENCE AG (DE) 2005-12-01 WO claimed
CN-114163401-A Preparation method and application of N-benzenesulfonyl formamidine compound 商丘师范学院 2022-03-11 CN disclosed
CN-114163401-A Preparation method and application of N-benzenesulfonyl formamidine compound 商丘师范学院 2022-03-11 CN disclosed
CN-114163401-A Preparation method and application of N-benzenesulfonyl formamidine compound 商丘师范学院 2022-03-11 CN disclosed
US-20080293674-A1 Azinyl Imidazoazine and Azinyl Carboxamide BAYER CROPSCIENCE AG (DE) 2008-11-27 US disclosed
EP-1751152-A2 AZINYL IMIDAZOAZINE AND AZINYL CARBOXAMIDE Bayer CropScience Aktiengesellschaft (DE) 2007-02-14 EP disclosed
WO-2005113553-A2 AZINYL IMIDAZOAZINE AND AZINYL CARBOXAMIDE BAYER CROPSCIENCE AG (DE) 2005-12-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080293674-A1 Azinyl Imidazoazine and Azinyl Carboxamide AZI2, NISCH, ZYX MMP2 4074/4885CA1 1447/4885CA2 317/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.