Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | CASP1 | P29466 | 1/20 | 0.64 |
| ▸ | CASP4 | P49662 | 1/20 | 0.64 |
| ▸ | CASP5 | P51878 | 1/20 | 0.64 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.60 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.60 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.60 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.60 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.60 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.60 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.60 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.60 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.60 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.60 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14351628 | 0.98 | ACHE (0.68) | ACHEALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL12511057 | 0.93 | ACHE (0.74) | ACHEALDH1A1KDM4EMEN1KMT2A | |
| Pyrrolidine SCHEMBL21177464 | 0.91 | ACHE (0.60) | ACHEALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL27397886 | 0.87 | ACHE (0.67) | ACHEALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9008678 | 0.85 | ACHE (0.65) | ACHEALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL4586698 | 0.85 | ACHE (0.69) | ACHEALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9621558 | 0.85 | ACHE (0.65) | ACHEALDH1A1KDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL2925348 | 0.84 | ACHE (0.63) | ACHEALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL249152 | 0.84 | MEN1 (0.52) | ACHEALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL8550826 | 0.83 | ACHE (0.74) | ACHEALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111655668-B | Improved process for the preparation of pyraclostrobin | GSP作物科学有限公司 | 2024-02-13 | — | — | CN | disclosed |
| US-11242320-B2 | Process for the preparation of Pyraclostrobin | GSP CROP SCIENCE PVT. LTD. (IN) | 2022-02-08 | — | — | US | disclosed |
| CN-103784458-B | Phenylalamine derivatives | AJINOMOTO K. K. (JP) | 2015-10-14 | — | — | CN | disclosed |
| EP-2547653-B1 | N-CARBOMETHOXY-N-METHOXY-(2-CHLOROMETHYL)-ANILINES, THEIR PREPARATION AND THEIR USE AS PRECURSORS FOR PREPARING 2-(PYRAZOL-3'-YLOXYMETHYLENE)-ANILIDES | BASF SE (DE) | 2015-01-28 | — | — | EP | disclosed |
| CN-102858735-B | N-carbomethoxy-n-methoxy-(2-chloromethyl)-anilines, their preparation and their use as precursors for preparing 2-(pyrazol-3'-yloxymethylene)-anilides | BASF SE | 2014-12-10 | — | — | CN | disclosed |
| CN-103784458-A | Novel phenylalanine derivatives | AJINOMOTO KK | 2014-05-14 | — | — | CN | disclosed |
| US-8642780-B2 | N-carbomethoxy-N-methoxy-(2-chloromethyl)-anilines, their preparation and their use as precursors for preparing 2-(pyrazol-3′-yloxymethylene)-anilides | BASF SE (DE) | 2014-02-04 | — | — | US | disclosed |
| EP-2547653-A1 | N-CARBOMETHOXY-N-METHOXY-(2-CHLOROMETHYL)-ANILINES, THEIR PREPARATION AND THEIR USE AS PRECURSORS FOR PREPARING 2-(PYRAZOL-3'-YLOXYMETHYLENE)-ANILIDES | BASF SE (DE) | 2013-01-23 | — | — | EP | disclosed |
| US-20130005986-A1 | N-Carbomethoxy-N-methoxy-(2-chloromethyl)-anilines, their preparation and their use as precursors for preparing 2-(pyrazol-3'-yloxymethylene)-anilides | BASF SE (DE) | 2013-01-03 | — | — | US | disclosed |
| CN-102858735-A | N-carbomethoxy-n-methoxy-(2-chloromethyl)-anilines, their preparation and their use as precursors for preparing 2-(pyrazol-3'-yloxymethylene)-anilides | BASF SE | 2013-01-02 | — | — | CN | disclosed |
| WO-2011113884-A1 | N-CARBOMETHOXY-N-METHOXY-(2-CHLOROMETHYL)-ANILINES, THEIR PREPARATION AND THEIR USE AS PRECURSORS FOR PREPARING 2-(PYRAZOL-3'-YLOXYMETHYLENE)-ANILIDES | BASF SE (DE) | 2011-09-22 | — | — | WO | disclosed |
| US-7557127-B2 | HDAC inhibitor | ASTELLAS PHARMA INC. (JP) | 2009-07-07 | — | — | US | disclosed |
| US-20090054464-A1 | HDAC INHIBITOR | ASTELLAS PHARMA INC. (JP) | 2009-02-26 | — | — | US | disclosed |
| US-7465731-B2 | HDAC inhibitor | ASTELLAS PHARMA INC. (JP) | 2008-12-16 | — | — | US | disclosed |
| EP-1776357-A1 | HYDROXYAMIDE COMPOUNDS HAVING ACTIVITY AS INHIBITORS OF HISTONE DEACETYLASE (HDAC) | Astellas Pharma Inc. (JP) | 2007-04-25 | — | — | EP | disclosed |
| US-20060052599-A1 | HDAC inhibitor | ASTELLAS PHARMA INC. (JP) | 2006-03-09 | — | — | US | disclosed |
| WO-2006016680-A1 | HYDROXYAMIDE COMPOUNDS HAVING ACTIVITY AS INHIBITORS OF HISTONE DEACETYLASE (HDAC) | ASTELLAS PHARMA INC. (JP) | 2006-02-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060052599-A1 | HDAC inhibitor | HDAC1, HDAC2, HDAC11 | ACHE 4051/4885ALDH1A1 1014/4885KDM4E 200/4885 |
| US-11242320-B2 | Process for the preparation of Pyraclostrobin | HPD, HPN, PPP3CB | ACHE 146/4885ALDH1A1 2439/4885KDM4E 151/4885 |
| US-20090054464-A1 | HDAC INHIBITOR | HDAC1, HDAC2, HDAC8 | ACHE 3895/4885ALDH1A1 739/4885KDM4E 195/4885 |
| US-20130005986-A1 | N-Carbomethoxy-N-methoxy-(2-chloromethyl)-anilines, their preparation and their use as precursors for preparing 2-(pyrazol-3'-yloxymethylene)-anilides | CBR3, CBR1, C1S | ACHE 3143/4885ALDH1A1 220/4885KDM4E 1059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.