Pyrrolidine

Pyrrolidine

SCHEMBL21177464

C1CCNC1.O=[N+]([O-])c1ccccc1CN1CCCC1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.60
ALDH1A1 P00352 6/20 0.56
KDM4E B2RXH2 5/20 0.56
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
POLB P06746 1/20 0.56
CASP1 P29466 1/20 0.56
CASP4 P49662 1/20 0.56
CASP5 P51878 1/20 0.56
CACNB4 O00305 1/20 0.54
CACNA1A O00555 1/20 0.54
CACNA1G O43497 1/20 0.54
CACNG3 O60359 1/20 0.54
CACNA1F O60840 1/20 0.54
CACNA1H O95180 1/20 0.54
CACNB3 P54284 1/20 0.54
CACNA2D1 P54289 1/20 0.54
CACNG7 P62955 1/20 0.54
CACNA1B Q00975 1/20 0.54
CACNA1D Q01668 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2372693 0.91 ACHE (0.70) ACHEALDH1A1KDM4EMEN1KMT2A
SCHEMBL9621558 0.90 ACHE (0.65) ACHEALDH1A1KDM4EMEN1KMT2A
SCHEMBL14351628 0.90 ACHE (0.68) ACHEALDH1A1KDM4EMEN1KMT2A
Hydrochloric Acid SCHEMBL2925348 0.88 ACHE (0.63) ACHEALDH1A1KDM4EMEN1KMT2A
SCHEMBL12511057 0.85 ACHE (0.74) ACHEALDH1A1KDM4EMEN1KMT2A
SCHEMBL27397886 0.79 ACHE (0.67) ACHEALDH1A1KDM4EMEN1KMT2A
SCHEMBL4586698 0.78 ACHE (0.69) ACHEALDH1A1KDM4EMEN1KMT2A
SCHEMBL9008678 0.78 ACHE (0.65) ACHEALDH1A1KDM4EMEN1KMT2A
SCHEMBL4586707 0.77 SIGMAR1 (0.64) ACHEALDH1A1KDM4EMEN1KMT2A
SCHEMBL249152 0.77 MEN1 (0.52) ACHEALDH1A1KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111655668-B Improved process for the preparation of pyraclostrobin GSP作物科学有限公司 2024-02-13 CN disclosed
US-11242320-B2 Process for the preparation of Pyraclostrobin GSP CROP SCIENCE PVT. LTD. (IN) 2022-02-08 US disclosed
US-20200354322-A1 IMPROVED PROCESS FOR THE PREPARATION OF PYRACLOSTROBIN GSP CROP SCIENCE PVT. LTD (IN) 2020-11-12 US disclosed
CN-111655668-A Improved process for the preparation of pyraclostrobin GSP作物科学有限公司 2020-09-11 CN disclosed
WO-2019142107-A1 IMPROVED PROCESS FOR THE PREPARATION OF PYRACLOSTROBIN GSP CROP SCIENCE PVT. LTD. (IN) 2019-07-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200354322-A1 IMPROVED PROCESS FOR THE PREPARATION OF PYRACLOSTROBIN HPD, HPN, CPB1 ACHE 142/4885ALDH1A1 2649/4885KDM4E 141/4885
US-11242320-B2 Process for the preparation of Pyraclostrobin HPD, HPN, PPP3CB ACHE 146/4885ALDH1A1 2439/4885KDM4E 151/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.