Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | CRHBP | P24387 | 2/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.42 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | CDC25C | P30307 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23727742 | 0.84 | KCNH2 (0.46) | MEN1KMT2ANPC1RAB9ATDP1 | |
| SCHEMBL2479710 | 0.84 | TSHR (0.54) | MEN1KMT2AKCNH2TSHRSIGMAR1 | |
| Hydrochloric Acid SCHEMBL23728039 | 0.81 | RAB9A (0.50) | MEN1KMT2ANPC1RAB9ATDP1 | |
| SCHEMBL20380500 | 0.76 | CRHBP (0.59) | MEN1KMT2AKCNH2TSHRCRHBP | |
| SCHEMBL23727847 | 0.75 | CNR1 (0.39) | KMT2ANPC1RAB9ATDP1TSHR | |
| SCHEMBL4810294 | 0.74 | CRHBP (0.61) | TDP1KCNH2TSHRSIGMAR1CRHBP | |
| SCHEMBL16682369 | 0.73 | KCNH2 (0.67) | KMT2AKCNH2TSHRSIGMAR1CRHBP | |
| SCHEMBL15618795 | 0.72 | ALDH1A1 (0.51) | RAB9ACRHBPCRHR2 | |
| Oxalic Acid SCHEMBL11231251 | 0.71 | KCNH2 (0.59) | MEN1KMT2AKCNH2TSHRSIGMAR1 | |
| Oxalic Acid SCHEMBL11231282 | 0.71 | KCNH2 (0.59) | MEN1KMT2AKCNH2TSHRSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4100393-A1 | NAMPT MODULATORS | Cytokinetics, Inc. (US) | 2022-12-14 | — | — | EP | disclosed |
| WO-2021159015-A1 | NAMPT MODULATORS | CYTOKINETICS, INC. (US) | 2021-08-12 | — | — | WO | disclosed |