Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR3 | P29371 | 3/20 | 0.58 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.50 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.50 |
| ▸ | PREP | P48147 | 7/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | FAP | Q12884 | 4/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3308995 | 0.76 | CXCR5 (0.64) | PREP | |
| SCHEMBL379808 | 0.74 | CYP3A4 (0.60) | ITGB1ITGA4NSD2 | |
| SCHEMBL6452631 | 0.74 | TACR3 (1.00) | TACR3KCNH2 | |
| SCHEMBL5603305 | 0.73 | NSD2 (0.56) | PREPNSD2HDAC3HDAC1HDAC2 | |
| SCHEMBL8573837 | 0.73 | NSD2 (0.56) | PREPNSD2HDAC3HDAC1HDAC2 | |
| SCHEMBL29375172 | 0.72 | KDM4E (0.56) | NSD2 | |
| SCHEMBL228713 | 0.72 | KDM4E (0.56) | NSD2 | |
| SCHEMBL14740657 | 0.72 | PREP (0.57) | TACR3PREPNSD2FAP | |
| Hydrochloric Acid SCHEMBL28349289 | 0.72 | NSD2 (0.55) | PREPNSD2HDAC3HDAC1HDAC2 | |
| SCHEMBL30135587 | 0.71 | NSD2 (0.62) | PREPNSD2HDAC3HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011119704-A1 | TRPV4 ANTAGONISTS | GLAXOSMITHKLINE LLC (US) | 2011-09-29 | — | — | WO | disclosed |