SCHEMBL23728846

SCHEMBL23728846

CCCNC(=O)CCNC(=O)O

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CASP2 P42575 1/20 0.47
MCL1 Q07820 1/20 0.47
CNR1 P21554 3/20 0.44
KDM4C Q9H3R0 1/20 0.44
NAAA Q02083 1/20 0.44
EPHX1 P07099 1/20 0.43
FAAH O00519 5/20 0.42
CNR2 P34972 2/20 0.41
KMT2A Q03164 2/20 0.40
DNM1 Q05193 2/20 0.40
GAA P10253 1/20 0.40
MMP1 P03956 1/20 0.40
MMP2 P08253 1/20 0.40
MMP3 P08254 1/20 0.40
MMP9 P14780 1/20 0.40
HPGD P15428 1/20 0.40
MEN1 O00255 1/20 0.39
CTSD P07339 1/20 0.39
ALDH1A1 P00352 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL43354 0.85
SCHEMBL10173167 0.84 KMT2A (0.58) CASP2MCL1CNR1KDM4CNAAA
SCHEMBL23001125 0.84 CASP2 (0.71) CASP2NAAAEPHX1FAAHKMT2A
SCHEMBL28156347 0.83
SCHEMBL27787563 0.83
SCHEMBL27787561 0.83 MMP1 (0.48) MCL1KDM4CEPHX1MMP1MMP2
Propane SCHEMBL31494775 0.83 MMP1 (0.48) MCL1KDM4CEPHX1MMP1MMP2
SCHEMBL3351989 0.83 CASP2 (0.56) CASP2MCL1CNR1NAAAEPHX1
Hydrochloric Acid SCHEMBL11072255 0.83
Acetic Acid SCHEMBL10885571 0.80 MMP1 (0.46) MCL1KDM4CEPHX1KMT2AMMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4384506-A1 PROCESS FOR POLYAMIDE SYNTHESIS Design Therapeutics, Inc. (US) 2024-06-19 EP disclosed
US-20240050576-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE Design Therapeutics, Inc. 2024-02-15 US disclosed
US-20230149550-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE Design Therapeutics, Inc. 2023-05-18 US disclosed
WO-2023014793-A1 PROCESS FOR POLYAMIDE SYNTHESIS Design Therapeutics, Inc. (US) 2023-02-09 WO disclosed
EP-4100404-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE Design Therapeutics, Inc. (US) 2022-12-14 EP disclosed
WO-2021158707-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE Design Therapeutics, Inc. (US) 2021-08-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230149550-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE DMPK, DTYMK, MYCBP CASP2 4038/4885MCL1 3039/4885CNR1 4683/4885
US-20240050576-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE ZFX, GRN, F13B CASP2 4403/4885MCL1 3114/4885CNR1 4099/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.