SCHEMBL23729048

SCHEMBL23729048

Cc1ccccc1N1CCN(c2c(C(C)C)cccc2C(C)C)[C@@H]1C

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
ALOX15 P16050 1/20 0.39
TSHR P16473 1/20 0.39
C5AR1 P21730 9/20 0.38
ADRB1 P08588 2/20 0.36
FAAH O00519 1/20 0.35
MGLL Q99685 1/20 0.35
HPGD P15428 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13698771 0.85 GABRA1 (0.41) ALDH1A1ALOX15TSHRFAAHHPGD
SCHEMBL22753233 0.83 ADRB1 (0.47) ALDH1A1TSHRADRB1MGLLHPGD
SCHEMBL24631896 0.78 ALDH1A1 (0.40) ALDH1A1ALOX15TSHRC5AR1FAAH
SCHEMBL19449636 0.77 TSHR (0.40) ALDH1A1ALOX15TSHRC5AR1FAAH
SCHEMBL17169612 0.77 TSHR (0.40) ALDH1A1ALOX15TSHRC5AR1FAAH
SCHEMBL20146595 0.77 TSHR (0.40) ALDH1A1ALOX15TSHRC5AR1FAAH
SCHEMBL23015446 0.76 ALDH1A1 (0.42) ALDH1A1ALOX15TSHRC5AR1FAAH
SCHEMBL20365239 0.74 ALDH1A1 (0.40) ALDH1A1ALOX15TSHRC5AR1ADRB1
Hydrochloric Acid SCHEMBL1609149 0.74 ADRB1 (0.44) ALDH1A1ALOX15TSHRC5AR1ADRB1
SCHEMBL17857367 0.74 ADRB1 (0.42) ALDH1A1TSHRADRB1MGLLHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3858945-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2021-08-04 EP disclosed