Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26707719 | 0.81 | ALDH1A1 (0.45) | L3MBTL1POLBALDH1A1KDM4EBDKRB1 | |
| SCHEMBL13492941 | 0.81 | ALDH1A1 (0.53) | HSD11B1KMT2AL3MBTL1POLBMEN1 | |
| SCHEMBL14595383 | 0.78 | NPC1 (0.50) | HSD11B1KMT2AL3MBTL1POLBMEN1 | |
| SCHEMBL12337282 | 0.75 | KMT2A (0.49) | HSD11B1KMT2APOLBMEN1RAB9A | |
| SCHEMBL25819453 | 0.75 | POLB (0.43) | HSD11B1KMT2AL3MBTL1POLBALDH1A1 | |
| SCHEMBL84852 | 0.74 | HSD11B1 (0.55) | HSD11B1KMT2AMEN1RAB9AALDH1A1 | |
| SCHEMBL23730021 | 0.74 | ALDH1A1 (0.47) | L3MBTL1POLBALDH1A1KDM4E | |
| SCHEMBL8213345 | 0.73 | HSD11B1 (0.56) | HSD11B1KMT2APOLBMEN1RAB9A | |
| SCHEMBL14871086 | 0.73 | ALDH1A1 (0.47) | HSD11B1KMT2APOLBMEN1RAB9A | |
| SCHEMBL13622464 | 0.71 | HSD11B1 (0.47) | HSD11B1KMT2APOLBMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021155321-A2 | COMPOUNDS AND USES THEREOF | FOGHORN THERAPEUTICS INC. (US) | 2021-08-05 | — | — | WO | disclosed |