SCHEMBL23729328

SCHEMBL23729328

CCCSC1=C(C(=O)c2ccc3c(c2C)c(=O)n(CCC)c(=O)n3C)C(=O)CCC1

nearest known ligand 0.36

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HPD P32754 8/20 0.36
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
MAPT P10636 1/20 0.31
CYP2C9 P11712 1/20 0.31
PKM P14618 1/20 0.31
CYP2C19 P33261 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
ALDH1A1 P00352 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23729826 0.93 HPD (0.38) HPDCYP1A2CYP3A4CYP2D6MAPT
SCHEMBL23729824 0.90 HPD (0.37) HPD
SCHEMBL23729327 0.86 ALDH1A1 (0.38) HPDMAPTALDH1A1
SCHEMBL23729701 0.86 HPD (0.39) HPDSMN1; SMN2
SCHEMBL23729698 0.84 HPD (0.38) HPDL3MBTL1
SCHEMBL23729825 0.82 HPD (0.40) HPDPKMSMN1; SMN2
SCHEMBL23729879 0.82 HPD (0.38) HPDPKMSMN1; SMN2
SCHEMBL23729829 0.79 HPD (0.36) HPDPKMSMN1; SMN2
SCHEMBL23730135 0.77 HPD (0.40) HPDALDH1A1
SCHEMBL23729828 0.77 HPD (0.37) HPD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3858818-A1 TRIKETONE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF, AND HERBICIDE Shandong Cynda Chemical Co., LTD. (CN) 2021-08-04 EP disclosed